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Seville oranges question about effect on immunosuppressants

Posted by jodeej @jodeej, Aug 26, 2018

Have any of you done any research on Seville oranges? We were told that they are used in marmalade and that was about it. After doing some looking, I discovered that they are grown in Brazil and can be used in juice. Just about every container of orange juice I've picked up says that it's made with oranges from Brazil. Do any of you drink orange juice and if you do, can you find any made only with American fruit?
Blessings,
JoDee

Interested in more discussions like this? Go to the Transplants Support Group.

@tbirdmunchkin | @glinda | Oct 13, 2019
In reply to @contentandwell "@glinda Snow already? Do you live in Montana or CO? Thankfully we have not seen any..." + (show)
@contentandwell

@glinda Snow already? Do you live in Montana or CO? Thankfully we have not seen any yet here in NH.

Sorry to hear of your recent infections and arthritis, the perils of aging, but not bad when you consider the alternative. I hope whatever antibiotic they put you on will be effective.

That’s great that your heart is doing so well, and hopefully will for many years to come.
Have a good rest of the weekend, nice weather in NH.
JK

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Actually I live in mid west Wisconsin and we can actually get snow as early as the first of October the weather here is funny we can have 70 degree one minute and rain or snow the next we never know and I'm just waiting to hear what type of antibiotic I will be on as it will be my third round of antibiotic for the same problem so I'm hoping it works this time three weeks of this is enough for me will keep you updated on how I'm doing after I start the third round of antibiotics enjoy your beautiful weather there and have a great weekend
@ glinda

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1 reply
JK | @contentandwell | Oct 14, 2019
In reply to @glinda "Actually I live in mid west Wisconsin and we can actually get snow as early as..." + (show)
@glinda

Actually I live in mid west Wisconsin and we can actually get snow as early as the first of October the weather here is funny we can have 70 degree one minute and rain or snow the next we never know and I'm just waiting to hear what type of antibiotic I will be on as it will be my third round of antibiotic for the same problem so I'm hoping it works this time three weeks of this is enough for me will keep you updated on how I'm doing after I start the third round of antibiotics enjoy your beautiful weather there and have a great weekend
@ glinda

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@glinda Did you see where in CO last week the temperature plunged from 83 to 13 in 34 hours? Our temperatures in New England are pretty variable but that's really extreme.
JK

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1 reply
Mentor
Dana, Volunteer Mentor | @danab | Oct 14, 2019
In reply to @contentandwell "@glinda Did you see where in CO last week the temperature plunged from 83 to 13..." + (show)
@contentandwell

@glinda Did you see where in CO last week the temperature plunged from 83 to 13 in 34 hours? Our temperatures in New England are pretty variable but that's really extreme.
JK

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@contentandwell , JK i used yo live in New England also. And it was probably about 1976 one spring i never forget. It was a beautiful Jun day 80's sunshining just a perfect day. We woke up the next morning to probably about 6 inches of snow and bitter cold. That was when i lived in Rhode Island. It only lasted a few days but we used to have a saying in New England if you don't like the weather wait a minute it will change.

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JK | @contentandwell | Oct 14, 2019
In reply to @danab "@contentandwell , JK i used yo live in New England also. And it was probably about..." + (show)
@danab

@contentandwell , JK i used yo live in New England also. And it was probably about 1976 one spring i never forget. It was a beautiful Jun day 80's sunshining just a perfect day. We woke up the next morning to probably about 6 inches of snow and bitter cold. That was when i lived in Rhode Island. It only lasted a few days but we used to have a saying in New England if you don't like the weather wait a minute it will change.

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@danab definitely true. I remember a snow storm in mid-May, probably around that same time. It sticks out in my mind because we went to my niece’s confirmation and it was snowing! As typical, it was gone very quickly. We sure never had quite as extreme a drop as in CO though. My son moved to CO a year ago so I’m conscious of the weather there now.
JK

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cmael | @cmael | Oct 15, 2019
In reply to @rosemarya "@contentandwell, Both my Home with my kidney and my Home with liver packets recommend to "Avoid..." + (show)
@rosemarya

@contentandwell, Both my Home with my kidney and my Home with liver packets recommend to "Avoid alcohol". It also says that if you have any questions to discuss it with your transplant doctor.
At my annual checkup in April it was the kidney doctor who replied to my question, "How can I best keep my transplanted organs healthy as I enter my next 10 years. Without blinking an eye, he said to me, "Take your meds, get your routine labs, and no alcohol". There was no doubt what he was telling me!

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When I went for my one year checkup at Mayo after kidney transplant , she asked if we were going to celebrate with maybe a glass of champagne. It kind of also felt like a suggestion. My daughter, the donor was with. She told me that I must be taking good care of my kidney and maybe because my test results all looked so good, she felt it was ok. We did have lunch at Canadian Honker before we left and each of us had a glass of wine to celebrate. I've never been a drinker other than maybe a glass of champagne or wine at a wedding.

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Mentor
Rosemary, Volunteer Mentor | @rosemarya | Oct 16, 2019
In reply to @glinda "Hi @ Rosemary's, Sorry it's been awhile that I have been on here just wanted to..." + (show)
@glinda

Hi @ Rosemary's,
Sorry it's been awhile that I have been on here just wanted to check in have been trying to keep up on connect with all the posts and this one caught my eye on the starfruit also as I was never told that starfruit was off limits either with being a heart transplant patient but they never told me that pumelos were off limits either and pulmelos are an Asian grapefruit with the same enzymes as regular grapefruit and Seville oranges so I avoid the pulmelos and starfruit even though I Love them hope you are doing good my heart is still strong and doing beautiful it's hard to believe that I will be 9 years post transplant in three months time in January. I am doing much better since my accident last year I now walk with one cane only but working on getting away from using that all my other injuries have healed completely but am now dealing with arthritis in both my legs and knees do to my injuries have also been dealing with a couple of infections that don't want to go away so I just got back on Friday from mayo in Rochester and waiting for some results to come back to decide what antibiotic to go on and whether it will be oral or IV so it's been kind of a rough year for me hope you had a good summer I'm so not ready for winter as we haven't really had summer here and definitely no fall but we have had snow flurries yesterday as I said I just wanted to check in and let you know how I am doing hope you have a good weekend.
Thanks @glinda

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@glinda, It is good to hear your voice. You have come a long way. It is amazing that you are using only one crutch! I find it interesting that you dropped me a notification in a discussion about food because, well, we transplant folks do like to eat - especially when we are feeling well. And I am feeling well, and staying active as I enjoy my post transplant life.
I hope that by the time you get my reply, that you will have a resolution for the current infection. Am I corretct to assume that you can be treated locally (with Mayo oversight) for the infection?
Yes - Please, keep following the discussion groups. I invite/welcome your input anywhere - especially when there is a heart transplant related conversation. At nearly 9 years with your heart transplant, you are the expert. I look forward to hearing from you, soon.

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Mentor
Rosemary, Volunteer Mentor | @rosemarya | Oct 16, 2019
In reply to @cmael "When I went for my one year checkup at Mayo after kidney transplant , she asked..." + (show)
@cmael

When I went for my one year checkup at Mayo after kidney transplant , she asked if we were going to celebrate with maybe a glass of champagne. It kind of also felt like a suggestion. My daughter, the donor was with. She told me that I must be taking good care of my kidney and maybe because my test results all looked so good, she felt it was ok. We did have lunch at Canadian Honker before we left and each of us had a glass of wine to celebrate. I've never been a drinker other than maybe a glass of champagne or wine at a wedding.

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Good for you, @cmael! You and your daughter deserve to celebrate.

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Mentor
Teresa, Volunteer Mentor | @hopeful33250 | Oct 17, 2019
In reply to @glinda "Hi @ Rosemary's, Sorry it's been awhile that I have been on here just wanted to..." + (show)
@glinda

Hi @ Rosemary's,
Sorry it's been awhile that I have been on here just wanted to check in have been trying to keep up on connect with all the posts and this one caught my eye on the starfruit also as I was never told that starfruit was off limits either with being a heart transplant patient but they never told me that pumelos were off limits either and pulmelos are an Asian grapefruit with the same enzymes as regular grapefruit and Seville oranges so I avoid the pulmelos and starfruit even though I Love them hope you are doing good my heart is still strong and doing beautiful it's hard to believe that I will be 9 years post transplant in three months time in January. I am doing much better since my accident last year I now walk with one cane only but working on getting away from using that all my other injuries have healed completely but am now dealing with arthritis in both my legs and knees do to my injuries have also been dealing with a couple of infections that don't want to go away so I just got back on Friday from mayo in Rochester and waiting for some results to come back to decide what antibiotic to go on and whether it will be oral or IV so it's been kind of a rough year for me hope you had a good summer I'm so not ready for winter as we haven't really had summer here and definitely no fall but we have had snow flurries yesterday as I said I just wanted to check in and let you know how I am doing hope you have a good weekend.
Thanks @glinda

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It is so good to hear from you, @glinda! It is amazing how you have recovered from both your transplant as well as your serious accident. Congratulations! I know that you put a lot of effort and thought into both recoveries.

I'm sorry to hear of the snow flurries. We are expecting them sometime soon in Michigan as well. Will you keep in touch?

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Mentor
Rosemary, Volunteer Mentor | @rosemarya | Jan 11, 2020

This morning I came upon this Consumer Health article as I was browsing through the Mayo News Network daily features. And since we have been talking about Seville oranges and a variety of foods that can affect our immunosuppresant medications I decided to share this with everyone.
- Consumer Health: Is your daily dose of citrus interfering with your medications?
https://newsnetwork.mayoclinic.org/discussion/consumer-health-is-your-daily-dose-of-citrus-interfering-with-your-medications/
I clicked the "Learn more from Katherine Zeratsky, a Mayo Clinic registered dietitian nutritionist, about the way grapefruit and other citrus fruits may interact with your medications."
Here it is - I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/food-and-nutrition/faq-20057918
I was surprised at the list of conditions (in addition to transplant) that are treated with medications that can interact with grapefruit.

What are your thoughts after reading this information?

REPLY
1 reply
JK | @contentandwell | Jan 11, 2020
In reply to @rosemarya "This morning I came upon this Consumer Health article as I was browsing through the Mayo..." + (show)
@rosemarya

This morning I came upon this Consumer Health article as I was browsing through the Mayo News Network daily features. And since we have been talking about Seville oranges and a variety of foods that can affect our immunosuppresant medications I decided to share this with everyone.
- Consumer Health: Is your daily dose of citrus interfering with your medications?
https://newsnetwork.mayoclinic.org/discussion/consumer-health-is-your-daily-dose-of-citrus-interfering-with-your-medications/
I clicked the "Learn more from Katherine Zeratsky, a Mayo Clinic registered dietitian nutritionist, about the way grapefruit and other citrus fruits may interact with your medications."
Here it is - I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true?
https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/food-and-nutrition/faq-20057918
I was surprised at the list of conditions (in addition to transplant) that are treated with medications that can interact with grapefruit.

What are your thoughts after reading this information?

Jump to this post

@rosemarya That is a very surprisingly long list of medications that grapefruit interferes with. It also says "Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications.", but beyond specifying Seville oranges it does not say what others yet it seems to indicate that it is not just Seville oranges. I enjoy clementines at this time of the year and presume they are not a problem, I hope not.
I got curious about Seville oranges so I looked them up. Apparently they are very bitter/sour so not generally eaten as a fruit but used in marmalades, etc. They are a cross between pomelos and mandarins so that must be why they are excluded -- pomelos of course are a variety of grapefruit.
JK

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