1. < Neuropathy

B-6 vitamin danger!

Posted by Lynsorensen @lynsorensen, Dec 11, 2017

With the assistance of a neurologist at Mayo Clinic, I have almost completely eliminated the uncontrolled muscle spasms now. First and foremost: beware of taking multi-vitamin capsules that have B6 listed. B-6 overdosage (which is contained in every multivitamin I found in stores and on the internet) can cause loss of muscle control and spasms in some people. So can gluten found in many foods so now I am also gluten free. I now work out with a personal trainer 3 days a week and do water aerobics another 2 days. Got off gabapentin and also clonazepam. Using CBD oil capsules each morning (no more opioids or chemicals) and using a CBD topical ointment to rub on my leg muscles each night. He says I don't need him anymore! And I don't. No more shaking or muscle cramps or pain. Still a little numbness but that is receding also.

Interested in more discussions like this? Go to the Neuropathy Support Group.

Hank | @jesfactsmon | May 24, 2020
In reply to @sunnyflower "Hello HankB, I am late in the game so please forgive if I am asking too..." + (show)
@sunnyflower

Hello HankB, I am late in the game so please forgive if I am asking too much. Has it been determined that B6 should be at a certain level and that there is an established amount we should take or not exceed in our supplements, or it can or will worsen our neuropathy symptoms? I apologize I just don't feel good enough to absorb all the info. Blessings, Sunnyflower

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Hi @sunnyflower, I am of course no doctor but the literature online mostly seems to indicate that most people don't need more than 2mg per day of B6. At some amount over that B6 could become toxic and possibly cause neuropathic symptoms according to some health websites. So my wife and I are starting to take the supplement I linked to earlier, 1 Body Vitamin B Complex, for the reasons stated in my earlier post. Previously we were happy with what we were taking but now we know that brand has 25 mg per capsule and so we have switched. Best, Hank

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Mentor
John, Volunteer Mentor | @johnbishop | May 24, 2020

@jesfactsmon, @sunnyflower, @stefspad, @keb, and others searching for vitamin B6 information. The following links were posted earlier in the discussion but I thought I would repeat them here in case you haven't seen them.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
— https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
— http://n.neurology.org/content/90/15_Supplement/P4.021

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1 reply
lioness | @lioness | May 24, 2020
In reply to @johnbishop "@jesfactsmon, @sunnyflower, @stefspad, @keb, and others searching for vitamin B6 information. The following links were posted..." + (show)
@johnbishop

@jesfactsmon, @sunnyflower, @stefspad, @keb, and others searching for vitamin B6 information. The following links were posted earlier in the discussion but I thought I would repeat them here in case you haven't seen them.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
— https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
— http://n.neurology.org/content/90/15_Supplement/P4.021

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@johnbishop Good article,s in there John especially the one about Osteoporosis

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sunnyflower | @sunnyflower | May 24, 2020

Thx very much John and lioness. Appreciate it. Overwhelming for my brain in the degree of pain I 'm in that literally makes me fight for my sanity. Just info, not a complaint. I' m blessed beyond measure! Basking in the unfathomable love of Christ, Sunnyflower

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1 reply
Hank | @jesfactsmon | May 25, 2020
In reply to @sunnyflower "Thx very much John and lioness. Appreciate it. Overwhelming for my brain in the degree of..." + (show)
@sunnyflower

Thx very much John and lioness. Appreciate it. Overwhelming for my brain in the degree of pain I 'm in that literally makes me fight for my sanity. Just info, not a complaint. I' m blessed beyond measure! Basking in the unfathomable love of Christ, Sunnyflower

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That is great that you have a strong faith @sunnyflower. With all the stupidity in our world today, with people arguing about ridiculous things, politics, etc., I just wish most people appreciated how good their lives are and enjoy the blessings of just being able to live without suffering as some such as you do, I think their lives would be infinitely better. You are an inspiration and I am glad to hear you describe the strength that your faith gives to you. All the best to you.

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1 reply
sunnyflower | @sunnyflower | May 25, 2020
In reply to @jesfactsmon "That is great that you have a strong faith @sunnyflower. With all the stupidity in our..." + (show)
@jesfactsmon

That is great that you have a strong faith @sunnyflower. With all the stupidity in our world today, with people arguing about ridiculous things, politics, etc., I just wish most people appreciated how good their lives are and enjoy the blessings of just being able to live without suffering as some such as you do, I think their lives would be infinitely better. You are an inspiration and I am glad to hear you describe the strength that your faith gives to you. All the best to you.

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Thank you for your kind words Hank!

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azgama | @azgama | May 26, 2020
In reply to @johnbishop "Hello @linnythepoo - I love that user name! Welcome to Mayo Connect - I'm happy you..." + (show)
@johnbishop

Hello @linnythepoo - I love that user name! Welcome to Mayo Connect - I'm happy you found us. It is a great place to ask questions, share your health concerns and learn what others with similar health issues are doing for treatment. Yikes is right from my perspective but I have no medical training or background. I would want to get an opinion or see a neurologist first.

Have you received a diagnosis of a form of neuropathy from a neurologist or had any tests to confirm the diagnosis?

I had a roundabout discussion through a 3rd party who I asked to check out a list of supplements that I'm taking for my peripheral neuropathy and this person giving the opinion was a neurologist. They said meh to my supplements and said they would probably recommend Metanx which contains L-methylfolate calcium, an active form of folate, and other essential B vitamins (B6 and B12) instead. B12 is in my list of supplements but I had already heard some bad stuff about B6 so I filed her opinion away under the category - it's my body, my decision. It's really a good idea to learn everything you can about your health condition and any drug used for treatment paying close attention to any side effects. I don't have any medical training or background so this is just based on my opinion and how I've dealt with my own idiopathic small fiber peripheral neuropathy.

Here's a more reliable source from the University of Virginia Health System - Peripheral Neuropathy and Vitamin B6 (PDF):
https://cancer.uvahealth.com/images-and-docs/neuropathy.pdf

Hope this helps,
John

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So is B12 ok to take?

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1 reply
Mentor
John, Volunteer Mentor | @johnbishop | May 26, 2020
In reply to @azgama "So is B12 ok to take?" + (show)
@azgama

So is B12 ok to take?

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Hello @azgama, Welcome to Mayo Clinic Connect. Here is some information from Mayo Clinic on vitamin B-12 that may help -- https://www.mayoclinic.org/drugs-supplements-vitamin-b12/art-20363663. Also the National Institutes of Health Office of Dietary Supplements has a Factsheet for Consumers here: https://ods.od.nih.gov/factsheets/VitaminB12-Consumer/.

Can I ask what made you decide to find out more about Vitamin B-12?

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1 reply
steeldove | @steeldove | May 26, 2020

Regarding the discussions about B6 and B12, it's important to remember that every individual is different, and our individual need for those B vitamins and other vitamins is different. Some of us need more than the suggested daily allowance.

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1 reply
helennicola | @helennicola | May 26, 2020
In reply to @steeldove "Regarding the discussions about B6 and B12, it's important to remember that every individual is different,..." + (show)
@steeldove

Regarding the discussions about B6 and B12, it's important to remember that every individual is different, and our individual need for those B vitamins and other vitamins is different. Some of us need more than the suggested daily allowance.

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so true but many articles state that most people derive enough B vits. from the food they eat; so should we be taking more even if our labs show a normal range? I’ve gotten the sense here that if you have a form of neuropathy you should be taking B12, so I have been confused as to whether or not supplementing actually can help if you have no deficiency which caused your problem. Helen

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