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Anyone have experience with new fibromyalgia drug Tonmya that came Aug

Posted by jeannesf1 @jeannesf1, Nov 3, 2025

Is Tonnya already prescribed by doctors?

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binblessed | @binblessed | Sep 14 7:15am

TONIX COUPON I HAVE UMR PRIMARY AS INSURANCE FROM HUSBANDS INSURANCE.

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debdourte | @debdourte | Sep 15 4:38pm

I think they say "sublingually" rather than "subliminally" to mean under the tongue... I fear I'd be on a lot more drugs if I could take them subliminally. Might reduce my prescription expenses considerably. I haven't tried cyclobenzaprine, but have taken low-dose Naltrexone at 4.5mg... obliterated my budget but did nothing for pain over a course of 3 months. Currently tizanidine and pregabalin at night, and duloxetine in the morning works best. That doesn't mean the symptoms all settle down, of course, different maladies flare-up from time to time (okay daily)... but I'm alive. I know my entire physical well-being would improve if I would just do the darned PT exercises, go for a walk and not succumb to chocolate cravings... but we all cope the best we can. I've been paying for Planet Fitness for about 5 years and been twice... I guess I'd better start stepping up to that, and I'll be better off. (Some days the THOUGHT of moving is painful!). Hang in there! Follow your doctor's advice and treatments and be honest with them about the results; together you'll find the best solution for you. Remember ... Nothing is perfect. Less pain is better than more pain even if we don't get all the way to "no" pain, fatigue, fog or flatulence... (whoopsie!)

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jeanninec | @jeanninec | Sep 28 4:41am
In reply to @daisy17 "Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the..." + (show)
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Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the market for years as a muscle relaxant. It's available as a low cost generic. Tonmya is that same drug reformulated to a lower dose (2.5mg I think) and taken subliminally rather than as a pill you swallow. By reformulating the drug, the drug company can charge lots more money (approximately $250 per month.). When I have a fibro flare, I take a 5mg tablet of cyclobenzaprine (lowest dose available) before bed. I think it helps with sleep and pain.

An article by Pradeep Chopra, MD (a Harvard-trained pain medicine specialist with over 25 years of experience treating complex chronic pain and multisystem disorders) said: "In summary, sublingual cyclobenzaprine (Tonmya) is essentially a repackaged low‑dose formulation of cyclobenzaprine, marketed as a novel drug through its patented delivery system. Its pharmacokinetic differences are small, its clinical benefit is modest and comparable to existing oral formulations, and its unique adverse effects may outweigh the theoretical advantage of reduced metabolite formation. Clinicians should therefore critically evaluate manufacturer claims and consider whether simple, low‑dose oral cyclobenzaprine would provide equivalent benefit at far lower cost."

I also take low-dose Naltrexone which has helped me tremendously. It has to be purchased from a compounding pharmacy and isn't covered by insurance. You slowly work up to a maintenance dose of 4.5mg. There are very few side effects and it takes a few months on the maintenance dose to notice results.

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@daisy17
Were you on opioids before this?

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sberg | @sberg | Oct 1 8:18am
In reply to @clm6 "I’ve taken cyclobenzaprine for years but carefully and sparingly. If I take it for several nights..." + (show)
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I’ve taken cyclobenzaprine for years but carefully and sparingly. If I take it for several nights in a row I will for certain have several days of a bad flare. So I’m surprised to hear that it’s being used as a treatment.

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@clm6 I've found the stuff to be worthless

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sberg | @sberg | Oct 1 8:20am
In reply to @ssnyder1990 "@daisy17 I think you mean sublingual which is under the tongue. Subliminal is by brain waves...." + (show)
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@daisy17
I think you mean sublingual which is under the tongue. Subliminal is by brain waves. So it’s an old drug to look new.

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@ssnyder1990 The old drug helps me the most. I tried the new and it didn't help a bit.

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leoandbear | @leoandbear | Oct 2 12:36pm
In reply to @sberg "@ssnyder1990 The old drug helps me the most. I tried the new and it didn't help..." + (show)
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@ssnyder1990 The old drug helps me the most. I tried the new and it didn't help a bit.

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@sberger61
Hi all!
Our bodies, treatments and pains are all so extraordinarily different. I’ve been on Tonmya for 2 months (Fibro 25 years). I’d like to say my daily ability to get out of the house for 3 hours a day has been great. Now having this for so long makes me skeptical of everything where my body is concerned. I started it when summer started so is it the drug or the sunshine? I guess I’ll know when winter is here in Oregon. I guess I also wanted to say try the meds that are developed for Fibro first. Some work 4 you some won’t. Maybe you’ll try off label meds, shockwave, chiropractic, acupuncture or all the alternatives out there. I’ll check in Dec. to let all know. Don’t dismiss something that doesn’t work for someone else. Let’s keep on plugging away…😸. Oh yes, a cat on my lap is my therapy also 🐈 🐈‍⬛.

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marci516 | @marci516 | 3 days ago

Hello,
I have PMR & now FM as a result of long covid. Along with other meds I do take LDN & am also taking Tonmya. I started taking it regularly a few weeks ago at bedtime and it is truly helping. My rheumatologists specializes in all issues listed above. She is with a major hospital and I feel fortunate that she has knowledge of the latest treatments available. I've had no negative side effects and have been able to decrease my Lyrica, which I don't tolerate well.

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hannahgjustice | @hannahgjustice | 1 day ago
In reply to @jeannesf1 "@lisa87 I can honestly say I’ve gotten better! Of course I wish I didn’t have any..." + (show)
Profile picture for jeannesf1 @jeannesf1

@lisa87 I can honestly say I’ve gotten better! Of course I wish I didn’t have any symptoms and the energy of a 15 year old (I’m 67) but your question makes me realize that I’m doing amazing as compared to when first diagnosed and years afterwards. I’ve was diagnosed about 17 years ago. I’m off Cymbalta and gabapentin and only on LDN 6 mg, heating pad, biofreeze and occasionally ibuprofen and faith in God! Using magnesium glycinate for sleep. (Right now sleep is good but usually really bad). My energy runs out by early noon but can keep going if I have to. I’m in process of changing my diet (from bad to good) so hopefully that will also help. I know everyone is different however now that I think about it I didn’t think I would ever get to where I’m at right now. Peace, hope, love.

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@jeannesf1 I take cymbalta and lyrica for my fibromyalgia. Can I ask why you went of them and what your experience was before and after? I haven't tried LDN yet, but it's an option. It feels like a hassle to get it filled and $$$.

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jeannesf1 | @jeannesf1 | 1 day ago
In reply to @hannahgjustice "@jeannesf1 I take cymbalta and lyrica for my fibromyalgia. Can I ask why you went of..." + (show)
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@jeannesf1 I take cymbalta and lyrica for my fibromyalgia. Can I ask why you went of them and what your experience was before and after? I haven't tried LDN yet, but it's an option. It feels like a hassle to get it filled and $$$.

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@hannahgjustice I had so many reasons. 1) had started taking LDN and wanted to see if it worked by itself. 2) wanted to see if was affecting my ability to lose weight. 3) I was having memory issues and some people said Cymbalta fries your brain and gabapentin certainly effects memory 4) I had been taking it for over 18 years and I wondered if it was even helping. When I was on it I couldn’t get out of bed until 1-5pm. Now I WANT to and get out of bed around 8-9am. Real life changer to be off of it., My best advice to you if you ever decide to get off Cymbalta make sure you titrate correctly with guidance of a doctor that knows what they’re doing. I had horrible withdrawal and still long term effects from getting off too soon by doctor who knew nothing about titrating correctly off of it. LDN was working great for about 8 months ( my worse pain was hip and outer thighs and it went away completely with LDN to this day, but just had bad flare up migraine face jaw neck so it’s not a miracle drug. Am concerned about surgery and opioid use warnings with LDN so I’m working on that. The cost of the doctor and compounding pharmacy was surprisingly low compared to how much I thought it was going to be. Only the first doctor appointment was $130. The $20 month membership to keep doctor doing refills. Pharmacy/pills are about $80, but that’s for 3 months. All the best to you.

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ecmoandrrt | @ecmoandrrt | 56 minutes ago

I take Flexeril TID(Q8). I chew it as its a very small pill.

Drug makers change an isomer and resell it. MONEY MONEY MONEY. ;(
"Structural modification". Example: One isomer may provide the desired medical effect (the eutomer), while the other is inactive or less potent (the distomer). For instance, only (R)-albuterol (levalbuterol) provides bronchodilation, whereas the (S)-isomer can promote inflammation.

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