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Anyone with COPD taking Nucala (mepolizumab)? How did it help?

Posted by snoots @snoots, Dec 15, 2025

I started Nucala a month ago, it’s an injection once a month. Has anyone else taken the monthly shots, how did they help?

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kat1359 | @kat1359 | Aug 9 5:39pm
In reply to @bigbird1956 "@kat1359 I got out of the hospital on May 14th from my last exerbation (I've only..." + (show)
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@kat1359 I got out of the hospital on May 14th from my last exerbation (I've only had two and been hospitalized both times) and I've been keeping a daily journal. The heat doesn't really bother me but the humidity sure does. Just forces me to stay inside more 🙁 Well good luck to you!

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@bigbird1956
Hope this helps you avoid any more hospitalization. Touch base every once in a while!

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snoots | @snoots | Aug 9 9:59pm
In reply to @kat1359 "Did it do anything for day to day breathing?" + (show)
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Did it do anything for day to day breathing?

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@kat1359 I think it helps somewhat, but if it kerp me out of the hospital that is great. Will discuss this more with my dr next week. Thinking i may want try the nucala

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kat1359 | @kat1359 | Aug 10 11:31am
In reply to @snoots "@kat1359 I think it helps somewhat, but if it kerp me out of the hospital that..." + (show)
Profile picture for snoots @snoots

@kat1359 I think it helps somewhat, but if it kerp me out of the hospital that is great. Will discuss this more with my dr next week. Thinking i may want try the nucala

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@snoots
Keep me updated. Im going to talk to mine hopefully in the next month.

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drm9 | @drm9 | Sep 8 12:09pm
In reply to @kat1359 "Did it do anything for day to day breathing?" + (show)
Profile picture for kat1359 @kat1359

Did it do anything for day to day breathing?

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@kat1359 Yes, Nucala does help me with day to day breathing. I only wish that I had started it sooner.

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suzyq61 | @suzyq61 | Sep 14 7:47am
In reply to @snoots "@suzyq61 didn’t you have to have a blood test to see if you have the Eosinophils..." + (show)
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@suzyq61 didn’t you have to have a blood test to see if you have the Eosinophils in the lungs. I think it works the same as dupixent.

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@snoots yes I did, sorry been off the grid, it’s summer and been busy and the nucala helped me with all

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johannasr | @johannasr | Sep 14 9:33am
In reply to @hicopd "Just learned that Nucala is billed to Medicare B (yes, that is B as in Bravo)..." + (show)
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Just learned that Nucala is billed to Medicare B (yes, that is B as in Bravo) and then whatever secondary insurance you may have. I had thought since it appears to me to be a medication it would be Medicare D and/or whatever private drug coverage the patient had. Nope, after 2.75 days of getting the runaround from Nucala/GSK as well as my insurer and CVS Specialty pharmacy, I finally learned at the end of it that NO, just because it is something that is administered by syringe or auto-inject pen at home, it is NOT considered a drug and is medical care covered under Medicare B (hey why do rules have to make sense). So now that we have had a 3-way conference call that the insurer customer service person set up between me, her and the pharmaceutical company, we will have the company re-bill Medicare correctly, who will get the bill 1st and then send the statement of benefits to insurer to process and pay their portion and I should have a grand total of $0 copay! That sure is much more palatable than the $790+ per auto-inject pen that they had billed me for!

My message is if you have problems, ask that a conference call be set up with your insurer and the Nucala folks to try to straighten out the bill. Do NOT assume you have to pay whatever high amount you are billed. Also, even though it may appear to be a medication, it is NOT covered under prescription drug plans it is Medicare B!?!?!? Oh well, that seemed like time well spent ironing all of this out, and it helps any other patient, YAY!

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@hicopd , it's billed under B for boy only if you get the shot in Dr.'s office, otherwise, if you get your shots at home it's billed under D.

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bigbird1956 | @bigbird1956 | Sep 16 7:27am
In reply to @kat1359 "@bigbird1956 Hope this helps you avoid any more hospitalization. Touch base every once in a while!" + (show)
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@bigbird1956
Hope this helps you avoid any more hospitalization. Touch base every once in a while!

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@kat1359 I recently did a summary of my daily journal for my Pulmanologist. I've attached the file here. It outlines the difference I have experienced after each shot.

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john2564 | @john2563 | Sep 17 9:41am

I was taking Dupixent for 6 months, it didn’t help me at all.
I’m now going on my 5th month of Nucala, I haven’t noticed any improvement as of yet. They say it can take up to 6 months to start working. I will let everyone know if it has helped me or not.
I just seen a thing on this spray for BreathiZen. But it’s not FDA approved. Wonder if I should try it?????

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bigbird1956 | @bigbird1956 | Sep 18 7:30am
In reply to @john2563 "I was taking Dupixent for 6 months, it didn’t help me at all. I’m now going..." + (show)
Profile picture for john2564 @john2563

I was taking Dupixent for 6 months, it didn’t help me at all.
I’m now going on my 5th month of Nucala, I haven’t noticed any improvement as of yet. They say it can take up to 6 months to start working. I will let everyone know if it has helped me or not.
I just seen a thing on this spray for BreathiZen. But it’s not FDA approved. Wonder if I should try it?????

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@john2563 Well if you looked at the attachment I sent regarding my progress month to month you can see that it has definately helped me! Just got my 4th shot yesterday. Sure hope you find something that will help.

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