Night time urination frequency post radiation

@climateguy
I am sorry to hear that it did not help : (. My husband is finishing his RT this week and 4 days back started waking up to pee 4 times (bladder was every time full BTW ). He also had more urgency when he had to wait for RT session to start so he asked his RO if that was normal and RO said that it is expected but prescribed him Myrbetriq which made ZERO difference. I bought him AZO 2 days ago and he now goes only 2 times at night and much less urgency today during RT. Since AZO has full effect after 2 weeks of use, I am sure that AZO will resolve his urgency and help speed up his recovery post RT. As with everything, we are all different - even with supplements. 🤷‍♀️ He is very happy that benign herbal supplement helped so much 🧿. He did not even change his diet or stopped drinking coffee etc.

@jeffmarc When you get up in the morning what is the amount of urine that you discharge? Regards from Over_age

@overage
I don’t measure it, but it’s usually a lot. I have an AUS and I have to press the bulb to pee when I get up in the morning. I have to press it four times before I’m done, each time I pee a lot and then it stops and I have press it to get it going again. During the day, I may only have to press it once.

@surftohealth88
It does take a couple of weeks before Myrbetriq starts to work well. We also have to take it twice a day for a couple of weeks. The longer I’ve been on it the better it seems to have worked.

@jeffmarc
Oh - thanks for telling me that 💗! I did not know about it nor we were told that- hah !!! Good to know in case that AZO stops working 😊 .

@surftohealth88
The fact that AZO works for you is really all you need to know.

You can.always try gemtesa if AZO stops working.

There were three different things called AZO when I last shopped for it. The active ingredient in the one the RO wanted me to take was phenazopyridine. I didn't think it was a herbal supplement. It turned my piss bright orange.

It sounds like we're all in a similar boat. I'm 68, Gleason 9, RP surgery in November 2024, 6-month Lupron injection October 2025 and 39 radiation treatments ending in March. I get up 3-4 times a night. At least the hot flashes from the Lupron are becoming less frequent. My next PSA test is in October. My cancer remains undetectable but my testosterone has not come back, <12. At diagnosis 26 months ago I thought I had an "easy" cancer and would be back to normal quickly. It's looking more and more like this is my new life. I appreciate the comments on this site. Very helpful.

I had ADT, brachy and IMRT back in 2018, and I've had trouble with frequency of urination ever since. They forewarned me prior to beam (IMRT) radiation, that if I didn't consistently arrive for each daily treatment with a full bladder, future bladder issues could occur.

I did my very best with it each morning, but it was difficult, and for at least a year afterwards, I was up at night as many as 8-10 times! So oneday, I had my local VA doctor do a comparative volumetric ultrasound of the bladder (scanned both full and empty). It indicated that there was significant scar tissue present on the bladder itself (maybe as much as 20%), which limits its ability to expand. However, he felt that it was only a part of the problem - that other physiological changes from my treatments were also at-play.

In the end, he was correct, because in the 7-years since, if I restrict my overall fluid intake after 4-5 pm each day, then I'm way down from 8-10 episodes per night, to 2 or 3.

@anosmic1
My brother had six month Lupron shots at 77. It took him almost a year before his testosterone came back to fairly normal levels. This is not uncommon, that it takes nine months to a year just to get to a couple of hundred after Lupron. That’s why we encourage people use Orgovyx Since the testosterone comes back much quicker.

Did you have to have those salvage radiation treatments because your PSA started rising again after the RP? There is an option to get testosterone replacement therapy, but with somebody with a Gleason nine who’s had their cancer come back within a year that treatment is Likely to be problematic. Definitely get your testosterone checked with your PSA in October.

Some information from the PCa Commentary about this

Examples of the relationship of the duration of ADT exposure to subsequent recovery to their
original T levels after stopping ADT are as follows:
- After 3 - 9 months of ADT nearly all men fully recover by about 10 months;
- After 18 - 24 months of ADT only 60% fully recover by about 3 years; and
- After 36 months of ADT exposure only 50% fully recover by ~ 5 years.
It is clear that after receiving ADT for longer than 6-9 months many men never fully return to their
T baseline. This raises the very important question of whether it is safe to offer replacement
testosterone in symptomatic men who have been rendered persistently hypogonadal (<230
ng/dL).