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Night time urination frequency post radiation

Prostate Cancer | Last Active: 2 hours ago | Replies (43)

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Profile picture for anosmic1 @anosmic1

It sounds like we're all in a similar boat. I'm 68, Gleason 9, RP surgery in November 2024, 6-month Lupron injection October 2025 and 39 radiation treatments ending in March. I get up 3-4 times a night. At least the hot flashes from the Lupron are becoming less frequent. My next PSA test is in October. My cancer remains undetectable but my testosterone has not come back, <12. At diagnosis 26 months ago I thought I had an "easy" cancer and would be back to normal quickly. It's looking more and more like this is my new life. I appreciate the comments on this site. Very helpful.

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Replies to "It sounds like we're all in a similar boat. I'm 68, Gleason 9, RP surgery in..."

@anosmic1
My brother had six month Lupron shots at 77. It took him almost a year before his testosterone came back to fairly normal levels. This is not uncommon, that it takes nine months to a year just to get to a couple of hundred after Lupron. That’s why we encourage people use Orgovyx Since the testosterone comes back much quicker.

Did you have to have those salvage radiation treatments because your PSA started rising again after the RP? There is an option to get testosterone replacement therapy, but with somebody with a Gleason nine who’s had their cancer come back within a year that treatment is Likely to be problematic. Definitely get your testosterone checked with your PSA in October.

Some information from the PCa Commentary about this

Examples of the relationship of the duration of ADT exposure to subsequent recovery to their
original T levels after stopping ADT are as follows:
- After 3 - 9 months of ADT nearly all men fully recover by about 10 months;
- After 18 - 24 months of ADT only 60% fully recover by about 3 years; and
- After 36 months of ADT exposure only 50% fully recover by ~ 5 years.
It is clear that after receiving ADT for longer than 6-9 months many men never fully return to their
T baseline. This raises the very important question of whether it is safe to offer replacement
testosterone in symptomatic men who have been rendered persistently hypogonadal (<230
ng/dL).