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PSA INCREASE - IS IT OK?

Posted by cochuir @cochuir, 3 days ago

70 YEAR OLD, GLEASON 7 (4+3), RADIATION/BRACHYTHERAPY/ADT FINISHED JUNE 24. PSA OCT 25-0.344, JAN 26-0.136, FEB 26-0.151, MAY 0.162, AUG-0.179.
SHOULD I BE CONCERNED,IS THAT OK.

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diverjer | @diverjer | 2 days ago
In reply to @topf "@diverjer The 0.1 or 0.2 thresholds for recurrence are after surgery, since PSA has to be..." + (show)
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@diverjer The 0.1 or 0.2 thresholds for recurrence are after surgery, since PSA has to be essentially zero. After RT the criterion is nadir plus 2.

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@topf
Thanks, that makes things much clearer. Since I had surgery, I didn't know about nadir + 2.

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cochuir | @cochuir | 1 day ago
In reply to @brianjarvis "@cochuir The only recommendation would be to track testosterone and full bloodwork with every PSA test,..." + (show)
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@cochuir The only recommendation would be to track testosterone and full bloodwork with every PSA test, that way you’ll know if anything is trending in the wrong direction and can take quick action if it does.

And get a genetic (germline) test if you have the opportunity.

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@brianjarvis thanks Brian.

what is the correct testosterone reading?

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brianjarvis | @brianjarvis | 1 day ago
In reply to @cochuir "@brianjarvis thanks Brian. what is the correct testosterone reading?" + (show)
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@brianjarvis thanks Brian.

what is the correct testosterone reading?

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@cochuir There is no “correct” reading, just a standard age-based range.

It’s always helpful to get a baseline testosterone reading (along with PSA) in order to know what’s normal; then tracking them together each time, as testosterone drops, PSA should too. If they ever got out of synch - which happens with castrate-resistance - you’d want to know.

Have you had a DEXA scan?

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cochuir | @cochuir | 1 day ago
In reply to @brianjarvis "@cochuir There is no “correct” reading, just a standard age-based range. It’s always helpful to get..." + (show)
Profile picture for brianjarvis @brianjarvis

@cochuir There is no “correct” reading, just a standard age-based range.

It’s always helpful to get a baseline testosterone reading (along with PSA) in order to know what’s normal; then tracking them together each time, as testosterone drops, PSA should too. If they ever got out of synch - which happens with castrate-resistance - you’d want to know.

Have you had a DEXA scan?

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@brianjarvis Brian, noted ref testosterone.
Had a dexa scan some time ago, I have osteoprosis since I had colon cancer 2019. Due another dexa scan January 2027.

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