Anyone else experience stiff and weak muscles while on the medications

I am have been various inhalers for asthma + Bronchiectasis over the last 6 mo. - most recently a Trimbow inhaler which has different components (beclometasone dipropionate 100 mcg + fomoterol fumarate dihydrate 6 mcg +glycopyrronim bromide 12.5 mcg) but I have felt the same symptoms + aches in my shoulders + more searching for words and a feeling of general mental fog. I am not sure if this is a result of the steroids I am taking for my asthma or simply I am getting older (76).

@legacygsh1 I had the same experience while on meds. My primary pointed out that a chronic infection alone is enough to cause this, then add the rigors of multiple meds and their side effects plus challenged lungs. Her advice- keep moving, several times every day, no matter how slowly and rest as needed. My walks went from miles to mere yards, but once off the meds my stamina gradually increased. Oh, and EAT even when it doesn't appeal, especially protein

I have had muscle wasting due to (Big 3 mac treatment) weight loss which doesn't help the stamina needed to maintain strength and physical activity. Like you, I'm not as steady on my feet. Maybe this isn't your issue, but weight loss was a topic at my last ID Doctor appt, as BMI is under 19. Doc said to concentrate eating high density, high caloric food, as much as you can. Hoping to gain some muscle back eventually. I normally do two walks a day to try to maintain my strength, each walk only about a mile.

Muscle strength and flexibility def compromised and systemic achiness - I can barely go down to tie my shoes at times. Complicating it for me is that I relied on ibuprofen for joint issues but now cautioned against that due to liver load. I'm hoping continued activity keeps joint issues from becoming permanent. Have used topical NSAID with some success.

I lost over 20 lbs along with all my muscle in arms snd legs. I was very active with hiking and elevation, biking, kayaking etc. Got a bad flu in January and everything went down hill from there. I am seeing a physiotherapist now for hip, groin, knee and back pain. I also developed plantar facia just to add to the mix so yes have experience major muscle and weight loss. It’s enough when we are dealing with lung issues but now pain in body.
I am on two inhalers and shortly to be on cyprofloxen and tobramcyn so will see what it does to me then. I try hard to keep moving even 2 or 3 short walks a day and lots of stretching exercises

@legacygsh1 Yes, like you I am on Azithromycin, Ethambutol, Clofazimine & Arikayce for cavitary MAC. We dropped Rifampin when I started Clofazimine. I have been on these meds for over 2 years and the last 4 weeks or so I started having similar issues, weakness in my legs, soreness in my legs and arms and pain in my lungs and shoulders. I am also experiencing awful fatigue and increased SOB. I am not exercising like I was because of this. This is disappointing as I was doing pretty good on all these drugs for quite awhile.