Any hopeful stage 4 storries

Hello...stage 4, GS8, 4+4 here. 3 days in ICU with large blood clot Aug 2025. Left with a bottle of Eliquis and a PSA of 66. Appt with urologist a week later, DRE (hard lump, first time I heard "cancer") biopsy In Sept, 14 of 14 cores positive, cribriform present in all cores. Appt with radiation oncologist, appt with medical oncologist. Petscan October of 2025, prostate, lymph nodes, one suspicious bone spot. Spent the next few months educating myself, started ADT (Orgovyx and Zytiga with prednisone) Feb of 26. Switched Zytiga to Nubeqa June of 26. PSA is now 0.13, T is 6. 2nd pet scan May of 26 showed improvement. No radiation, no surgery. Dr says Pluvicto is in my future perhaps in 1 or 2 years or whenever the ADT quits working. Take your time, read all you can, ask questions here (and on other forums). Remember that each prostate cancer patient represents tens of thousands of dollars to the medical business model. You will have to advocate for yourself....you are in charge of your treatment. Quality of life is the driving factor for me, I am taking a conservative approach to my own treatment, at 72yo less stress is best, lol. Please know that you are not alone, we are all finding our way thru this complicated, confusing situation, educating yourself is the the first thing to do......thanks for reading my post, I will be reading yours!

Yes I feel for you but no worries
I had Gleason scores at 10
I have stage 4 prostate cancer to the bone
Going on 7 years
Been on xtandi for the whole time with a androgen therapy
Now going to radiation therapy for removing a few buggers that got out and caused some trouble but fixable.
Walk walk walk walk keep your strength up and never surrender
Free your mind change your focus

@james4511
Check out this recommendation

Running and prostate cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC12535562/
https://bioengineer.org/exercise-conditioned-serum-inhibits-prostate-cancer-growth/

On July 27, 2022, I was diagnosed with Stage 4 high-volume, bone-only metastatic prostate cancer. My initial scans lit up like a Christmas tree, and a bone biopsy confirmed the diagnosis. The pain in my spine, hips, and ribs was severe, but fortunately, the cancer has never spread to my organs or lymph nodes. My treatment was aggressive. I started with 30 days of bicalutamide, followed by Eligard injections, Darolutamide, and 10 rounds of chemotherapy instead of the standard six. I also had 10 radiation cycles to my spine and five to my ribs. Most recently, I completed 20 rounds of pelvic radiation for "clean-up" to improve long-term survival. The chemo phase was terrifying because my PSA fluctuated, causing my oncologist some concern. But 11 months after diagnosis, my PSA became undetectable—and it has stayed that way for four years now. My doctor calls me a "super responder." Before my diagnosis, I had my gallbladder removed. Doctors blamed all my pain on that and missed the cancer on early CT scans. It was a painful, difficult time, but I am glad it is behind me. Today, I embrace both science and faith. While adenocarcinoma affects us all differently, I credit Jesus for giving me the strength to endure treatments that made my cancer indolent. To maintain my strength and stay here for my family, I eat a plant-forward diet and push through physical therapy to rebuild muscle. Everyone’s journey is different, but I stand firmly in my faith that I am healed. There is always hope.

My first glimmer of hope came from my uncle. He's a retired physician and surgeon who still keeps up on the latest research. He has always been very blunt, and not sugar-coated anything. If you're going to die, he'll tell you straight out.

When my mother told him about my stage 4 bone-metastatic prostate cancer, he told her "Oh, he'll be fine." That's the first time I heard a medical person said I wouldn't be dying soon. Later, my radiation oncologist and family doctor started telling me the same thing. I was so prepared to die when during those long nights awake in the hospital bed, writing notes on my finances and insurance to help my family after I was gone, that it took a while to really trust it wasn't going to happen (at least, not any time soon). I still need reassurance sometimes, nearly 5 years later.

Things have changed that fast and that recently: I was diagnosed just as the change was happening at the bigger cancer research centres. I doubt patients now go through what I went through, but back then, they were still giving us the life expectancy stats from before new treatment approaches like doublet therapy, MDT, PDRT, etc.

Darolutamide (Nubeqa) is a miracle drug.

@wooldridgec Yes, all the 2nd generation ARSIs (so-called "-lutamides") are pretty amazing.

I had a psa of 240 .metastesis to bones, spine,lungs and lymph nodes.Had radiation,made positive changes and feeling quite well.Walk and work and exercise and appreciate and thank
God for every day.This disease opened my eyes.I have beaten one doctor's estimate of life expectancy.On adt s ,no chemo and enjoying life.Don't be afraid Christinadirson think positive

I had stage 4 mestatic prostrate cancer. It had spread to pelvic area shoulder and back. Jeff Marc encouraged me to see oncologist. As of now my last PET scan didn't show anything my last 5 Psa levels were undetectable. So as Jeff Marc says its now treatable. This is a very good support who are well informed and very encouraging. Im so thankful i found this support group.

Wow my psa was 59 and I thought that was high. Thank God for doctors and medicine today. Im so happy for you tonno.