GLP-1 agonists (Ozempic, etc.) to treat long-COVID?

Posted by roxannelee @roxannelee, Nov 15, 2025

Anyone know if health insurances will cover GLP-1 agonists to alleviate long-COVID? If not, anyone know the cost out of pocket for those meds?

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Profile picture for lpow276 @lpow276

Are there any preliminary results on the Scripps trial?

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@lpow276 - As mentioned, there are anecdotal results reported by individual participants. The study goes through next March or April, I think.

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Profile picture for vostie @vostie

@lpow276 Yes, a percentage of the people in the study with me are having good results and are concerned about losing the drug after the study. A percentage dropped out due to side effects (including weight loss) and some percentage dropped out to get the real GLP-1 as they felt they were on the placebo. I had initially had terrible insomnia all night on shot day but no other side effects so I am either on the placebo or am a GLP-1 non-responder. A good share of the 1000 participants are communicating on Facebook...but it is impossible to determine how many of us did well...just know a good number of people did well...probably at least 20%. Some did well on low doses but did not seem to do well on the higher doses. Some dropped out as they could not handle any more weight loss.

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@vostie what sorts of positive results have participants noticed? I read, for example, that some who micro-dosed tirzepatide lost or reduced their food sensitivities.

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Fatigue, brain fog, temperature fluctuations, pain, perm, shortness of breath, exercise intolerance, sleep, heart rate and mood have been mentioned.

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Profile picture for vostie @vostie

Fatigue, brain fog, temperature fluctuations, pain, perm, shortness of breath, exercise intolerance, sleep, heart rate and mood have been mentioned.

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@vostie sorry not perm, PEM

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I have Long Covid and started a GLP-1 in early July (8 weeks ago) and the results have been overwhelmingly great. The theory is Covid caused me to develop MCAS (saw 9 doctors in 4 years and my RD who I worked with for 2 years was the one to suggest what I had might be MCAS). My symptoms where not typical MCAS, I would get terrible pelvic and lower back pain, red eyes, burning pain while urinating, and debilitating fatigue. I also had gas and bloating that was off the charts. My weight went up and I simply could not do anything to bring it down.. my son-in-law who is a veterinarian suggested I take claritin, pepsid, and ask my dr for a GLP-1. I did all 3 and feel better than I have felt since 2022 (when I got Covid). For the first time in years I don't feel like I have an alien in my body. The meds come with side effects BUT if you are careful about what you eat, they are truly not bad.

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