Anyone else on Daraxonrasib (RMC-6236)?

@strongone21 Thanks.

My mom started Daraxonraspid three days ago. The only side effect we are struggling with is diarrhea. We are on day three of it and Imodium and Lomotil don’t seem to help. Anyone else having the same side effect? Is there anything that has helped?

I take 2 Imodium when it starts and 1 with each additional bout. Dre that I have to take more than 3. I like the gel caps.

Beware of sun exposure! Daraxonrasib can cause severe sensitivity to the sun. Even small mount can be flying in my experience.

@mimimmx

Sorry about all the typos. It is rare that I need to take more than 3 Imodium.

Even small amounts of an exposure can be problematic in my experience. Causes severe burning, rashes and sores/scabbing.

@mcoviello Hi and Welcome to Mayo Connect. Sorry to hear about your mom's journey. We do have some folks here that are taking Daraxonraspid. @mimimmx has fortunately shared some input. Hopefully, you can get some more feedback to learn from others taking it. How is your mom holding up in general?

@tomrennie thank you! The diarrhea has been the only major side effect so far. If we can get that under control things would be better. The Lomotil and Imodium aren’t as effective so we will check in with her doctor tomorrow.

@mcoviello Great idea on checking in with her doctor. Hopefully another more effective option will be discussed. Please let us know how the appointment goes ok? Since this is a new treatment, many folks are interested in learning through her experience. Thanks.