How are you managing Brukinsa side effects?

Posted by sveta25 @sveta25, Feb 6 12:35pm

My husband is taking Brukinsa for 3 weeks now and so far so good, no bad side affects, WBC is lower but so are platelets so minor bruising and also constipation.
Any comments on using it longer than that ?
TYIA

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Profile picture for Lori, Volunteer Mentor @loribmt

Welcome to Mayo Connect, @wigman50 There are so many members of our armed forces who are suffering the repercussions from Agent Orange. I’m sorry you’re one of them. I lost my brother many years ago from direct exposure to AO.
Thank you for sharing your experience with taking Brukinsa for your diagnosis of Mantle Cell Lymphoma. You mentioned taking Brukinsa for about 2 years. Has that been successful in keeping the condition under control for you?

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@loribmt My husband is on Brukinsa since January 2026, his WBC is 28 v. 210 before Brukinsa ( he was hospitalized in Jan.)however his hemoglobins in March was 7 so he had to have blood transfusion, now it’s 10, still low but better then before transfusion, his platelets are also low. He had some leg swelling but it’s OK now and he is feeling much, much better than before treatment. He also has some bruising on his hands.
Brukinsa does work and we hope it will keep his CLL steady.

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I've been on it for 2year's and 3 months. I have light-headedness and some bruising. Other than that no problem. Good luck and sending prayers and great vibes.

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