Treatment Resistant Depression: What can I do?

You could call David Careon, MD at the Acacia Clinic in Sunnyvale, CA. He was part of the inventor group that developed SAINT.
He also might be able to give you the name of facilities nearer to you that might offer it. When I did it, I went out to Sunnyvale to the Acacia Clinic. At that time (2022) it was considered experimental but had been approved by the FDA. It really turned things around for me.
But in the 4 years since, SAINT, I’m told, is available in major cities across the US. So, they might be able to administer it at the UK medical school. Contact the Dept. of Psychiatry. It also might be available in Cincinnati, OH at the school of medicine at the University of Cincinnati. Again, call the Dept. of Psychiatry.

I know it is also available in Boston, but I don’t know where.
I hope this helps. TRD is awful!

Dr. Carreon’s phone number is : 650-993-9996.
Take care.

California which is not helpful but you might call them and ask that very same question. Have you tried Auvelity???

@pfoster689
I have been looking into all the different kinds of TMS.... there are SO many.
As far as the SAINT Protocol goes, it appears (from my deep diving) that it is VERY limited because it is all dependent on being called SAINT due to the proprietary rules of the software. There are other options out there that work on similar platforms, TMS being "guided" more but do not use that specific program, so cannot be called SAINT. So, it looks like you'd have to go to California or I think there was a place in Utah ?
After all of my reading, and then a consultation with the Dr., I am going for my 1st TMS treatment at the end of the month. I have chosen to try the 1 Day treatment Protocol. It new and there isn't a lot of information out there on it (in comparison to the Standard or even Accelerated protocol). So far it looks to have reasonable results (70%'ish) in the 1-6week range....a shorter period of time then trying yet another medication. To me it's worth a shot at trying to feel better again.

I am interested in this treatment. Sunnyvale is quite close so more than doable.
The problem is this would not be for me but my husband. He has tried various modalities with really no changes. I did tell him about SAINT some time ago, probably Jan/Feb when I read about it on here. He thanked me for the info but has never said anything since. Part of his depression he has become so uncommunicative. I am hesitant because I know I can't do it for him and sometimes he is resentful if I ask or give him the information. He has been in a severe depression since he retired 10 years ago. I think he being a workaholic kept much of the depression at bay. I feel he also wants the magic treatment where it will just all go away.

@crabby55
Has he tried an MAOi (mono-oxidase inhibitor?) it works differently than SSRIs. During my post-partum depression, this felt like a miracle. I started at 15mg but soon went to 30 mg. It was amazing. I did have difficulty sleeping and was given amitryptiline which solved that problem. Many Dr.s say you cannot give both at the same time, but the Psychiatrist I worked with had recently returned from a year in England where that was done. I had no problems. I took Nardil (the MAOi) It can give a dry mouth but I did not have that reaction. One thing that is important—if you go off it for any length of time, it doesn’t work when you go back. I hope he tries this. Before seeing a new Dr., he should ask if they are willing to prescribe this medication. There are diet restrictions (no soy sauce, yoghurt and ??? The amitryptiline made that not an issue) so he would want to say that “he would be very compliant.” It doesn’t seem to be used much anymore but I hope he can get it. It is definitely worth trying!!!!

@crabby55
You can lead a horse to water ....
Does he acknowledge (as best he can) the severity of the depression?
Something a friend of my did (when discussion was not welcome) was print off some information/a brochure/book and just leave it on a table. If it's something he may be interested in, perhaps he will pick it up and have a glance at it.
I think we all/anyone who suffers from Depression would love to find that pill. Unfortunately it's hidden in a gold pot at the end of a rainbow.

@crabby55
I meant to add that it is wonderful you are looking out for him and doing what you can to support him. Whether he knows it or not, or acknowledges it to you .... he is a lucky man to have you.

@rufus31
ahhh, thank you. You hit the nail on the head on several points. I definitely am aware of leading the horse to water. My real question was wanting more of an opinion of what those of you are going thru. An opinion I've gotten , hope to get more and respect. It gives me insights as to some of the thought process. It's a fine line between helping and enabling. I'm not a great caretaker. I'll do up to a point. It is sad to see/watch your loved one become someone else and set themselves up for negativity.

To answer your question, I think he realizes the severity of his depression when it's convenient and in denial most the time. [the wishing it would just go away] I've said he is married to his depression. Isn't willing or completely unable to take steps or do the steps/tools he has been given thru outpatient/CBT etc.

@crabby55
Oh Boy .... I wish there was some explaining the thought process of a seriously depressed person. I am one and what my head does to me, what it makes me think and how absolutely almost impossible your own psyche makes it to take the steps you need to help yourself is mind boggling!
I am currently reading (well trying anyway) a book called 'Coping with Depression - From Catch 22 to Hope'. Everything a depressed person should do to try and help themselves is almost out of reach because of the depression....it really is a Catch 22 situation.
I hope somehow he will want to help himself, with the help of others....
It most certainly is not something most people can do on their own.