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Evenity and random hives

Posted by sandrac @sandrac, Jul 29, 2024

Has anyone else had random episodes of mild hives with Evenity? I have had 5 treatments so far and due another next week. Every now and then since #4 (going for days with no issues) I get itching and hives-like redness (but no whelps) mostly on arms and hands with a little on my chest that goes away with Allegra. I never had this before. Seeing doc Monday and will see if it is safe to continue as long as they stay at this level and Allegra takes care of. I have had no other discernible side effects and really hope to finish the sequence of 12.

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dbamos1945 | @dbamos1945 | May 12 3:36pm

Evenity is touted as the newest and best osteoporosis bone builder - consider the big picture before you throw in the towel. As you research the side effects of the rest of the osteoporosis medications, Evenity was my 1st choice. I had a little fatigue & bone twinges, but no other side effects for the 12 months.

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anon172 | @anon172 | May 12 4:38pm

Thank you for getting back to me.

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anon172 | @anon172 | May 12 6:13pm

Thank you for your reply. I hope that for you too.

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oopsiedaisy | @oopsiedaisy | May 12 7:06pm
In reply to @anon172 "My first Evenity injections on Feb 22, and on March 10, my eyes started burning and..." + (show)
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My first Evenity injections on Feb 22, and on March 10, my eyes started burning and itching, stye (still have) and swelling. On March 13, itching and hives every day. Constant. I feel sweaty too. Not right. My dr says it might not be Evenity and just allergies. I’m supposed to get my 4th injection next week. I’ve read a couple older posts re itching, but not many. Anyone else get ridiculous itching from Evenity? I’m just considering stopping.

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@anon172 I had some itching about 4 months into my treatment period. It gradually dissipated and it disappeared by the end of the 12 months.

My allergies this year have been the worst ever. My eyes burned and itched for weeks. I had to double up on my allergy medication.

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anon172 | @anon172 | May 13 10:24am

Thank you for getting back to me. Maybe this nightmare itch will go away or at least mellow out. Fingers crossed so I can continue.

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ciciriri | @ciciriri | 5 hours ago

I got my very first shot(s) on Monday, June 29, 2026. One shot on the back of each arm. I felt fine, until exactly 1 week later. Woke up Monday, July 6, 2026 with what I thought was a very bad mosquito bite on the back of my right arm, wrong! It was a bad rash on the location where the shot was given. It itched terribly, I also noticed that my left arm where the shot was given also had a rash but no itching. The next day I noticed that the rash got bigger, redder and warmer on both arms. No where else on my body do I have a rash or itching, just at the location of where the shots were given. I think this is normal as long as you do not have trouble breathing, or your face, lips etc. do not swell. My doctor said if I was willing to continue with Evenity, said yes. She advice me for the next shot(s) to take Zyrtec before coming in. This is scary as I am only 61.

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ciciriri | @ciciriri | 5 hours ago
In reply to @moon4kat "A few days after my 4th injections (in abdomen) I started getting itchy red bumps. At..." + (show)
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A few days after my 4th injections (in abdomen) I started getting itchy red bumps. At first I thought they were bug bites from working in the yard. But they -- clearly hives -- have spread all over my thighs, hips, legs and ankles, with a few on my upper torso and arms. The bumps have pustules and the itching is maddening. When I reported this to the nurse practitioner, she said she didn't think the outbreak was due to Evenity injections because of the timing. She thinks the reaction would be almost immediate, not days and weeks later. Has anyone else experienced an onset of hives several days after the injections?
Thanks.

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@moon4kat
Yes, I experienced hives / rash exactly a whole week later. They were only on the back of both arms, where the injections were given.

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