Getting second lupron injection

Posted by kevtrav @kevtrav, 5 days ago

Has anybody gone through rounds of lupron injections? I had my first shot st the end of February. I've experienced severe fatigue, mood swings, tears come easily, muscle loss, weight gain, brain fog and more. I have my second shot in early September. If you've had this, does your body handle the second shot better? Does the fatigue and side effects hit you hard again?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for maga @maga

After 2 injections of Lupron and 23 radiation treatments, I was very exhausted. I so fed up with feeling this way I became angry. I went home, put on my swim suit and went swimming in the local salt water lagoon. Since I was out of shape for swimming I only swam about 200 yards. ( I gradually work up to 1000 yards.) When I got out of the water I felt about 70% of my energy came back along with a better attitude. I attribute this to breathing deep with each stroke which injects oxygen into the blood stream. I had 2 years of Lupron and went thru a lot of what you are going thru. My last injection of Lupron was last March. Most of the bad experience is leaving. I am 87 years old and still swim in the summer, lift weights twice a week and run up 3/12 flights of stairs as fast as I can twice a week.
I'm a firm believer in exercise to relieve much of the negative things you mentioned.

Jump to this post

@maga You're an inspiration!! Good for you!
I workout pretty regularly and walk my dog every day, which has helped with the fatigue.

REPLY
Profile picture for kevtrav @kevtrav

@brianjarvis I was told of "some" of the side effects. When I felt something new, I'd search it and see that it was a side effect of the ADT.
I do workout and walk, which has helped.

Jump to this post

@kevtrav That’s unfortunate that you were only told about “some” of the side-effects.

There has been much reported on the physical benefits of resistance-training exercise while on ADT. Here are just a few that I’ve bookmarked:

> Drs. Sholz and Moyad talking about exercise and hormone therapy: https://m.youtube.com/watch

> A paper on The Benefits of Exercise During Hormone Therapy: https://static1.squarespace.com/static/54c68ac6e4b06d2e36a4b8c9/t/55cb7275e4b0d97ae7ff60af/1439396469154/The+Benefits+of+Exercise+During+Hormone+Therapy_Insights+August+2015_PCRI.pdf

> A study about the benefits of exercise to counteract the adverse effects of ADT: (They describe a good resistance-training program): https://journals.lww.com/acsm-msse/fulltext/2023/04000/resistance_exercise_training_increases_muscle_mass.2.aspx

REPLY
Profile picture for kevtrav @kevtrav

@jeffmarc You're doing everything right! I really appreciate your detailed response!
I workout pretty regularly- weights and then walking my dog daily for at least 2 miles.
I'm already on anti-depressants because my wife has had early-onset dementia for 9 years. She's my top priority.
I've put on 10-12 pounds and all it seems in my belly.

Jump to this post

@kevtrav
One of the first things ADT does is weaken, the stomach muscle muscles, resulting in a belly. Your problem may not be mainly in the stomach, It may just be ADT’s effect.

I weigh myself every day in order to make sure I don’t gain weight. I base what I eat on what I weigh. If you don’t keep a real close track of it, you gain a few pounds and then it is very hard to lose it. I did gain 6 pounds over the holidays last year and it took me four months to lose them.

Low T causes a sluggish metabolism, reduced muscle mass, increased abdominal fat storage, and low energy for exercise. Low-T creates a cycle where weight gain further lowers testosterone, requiring lifestyle changes or medical intervention to break.

Cutting out meals for weight loss often backfires by causing your metabolism to slow down and promoting fat storage as the body enters a survival-oriented "conservation mode". It leads to nutrient deficiencies, intense hunger causing overeating later, energy crashes, mental fatigue, and potential muscle loss.

Between low T and the inability to cut out meals. It’s really annoying how hard it is for prostate cancer patientsto lose weight. When it comes down to is we really need to change our diets.

REPLY
Profile picture for kevtrav @kevtrav

@surftohealth88 I'm not sure. I've kind of been winging it throughout the whole ordeal. My wife has had early-onset dementia for 9 years, so she is my top priority.
I do workout pretty regularly and that seems to help.

Jump to this post

@kevtrav
Oh boy - I am soooo sorry to hear that : (((. Sending you my best wishes and blessings 💗, it must be tremendously hard *sigh, and kudos to you for managing both your and your wife"s care. Try to get Orgovyx if you can, perhaps it will help.

REPLY
Profile picture for Jeff Marchi @jeffmarc

@guybe
I was never into exercise before ADT. After I started ADT, I didn’t exercise for the first five or six years. First, I started walking every day, At least a couple of miles, As fast as I could go.

Then I found out I couldn’t get off the floor without pulling myself up on something.That started me going to the gym 3 days a week. That enabled me to stand up without holding on.

I never did have fatigue or mood issues, so I didn’t need to do the exercises in order to reduce the those problems..

Everybody reacts differently to ADT. I also wasn’t getting informed about the benefits of exercise, Unless you participate in some prostate cancer groups, you don’t hear about the need to exercise.

Jump to this post

@jeffmarc Exercise won't get the attention it needs among the ADT "community" until MOs actively encourage it as a basic part of treatment, even to the extent of tracking their patients' physical activity. Prednisone, despite its known dangers, is prescribed along with abiraterone in order to promote some level of energy among ADT patients. And yes, it's necessary, no argument there. So why not give the same level of treatment emphasis to activity that is entirely beneficial, costs nothing, gets no argument from insurance companies, and supports the same results? Maybe MOs just have an easier time getting pills to be swallowed than weights to be lifted, and they don't want to cause resistance to the former by insisting on the latter.

REPLY

This website has been helpful and depressing at the same time . So many men are suffering mentally and physically, the. To have you wife dealing with early signs of dementia has to be overwhelming. Actually I think my wife is also showing signs but if I say anything like I just told you 10 minutes ago I’m in the dog house .i have to be careful what and when I say anything. I caught her ordering pills for memory loss but then she cancelled it , knowing it would not help even though that billionaire invested millions to develop the pill, wish you luck with all the stress.

REPLY
Profile picture for graybeard46 @graybeard46

This website has been helpful and depressing at the same time . So many men are suffering mentally and physically, the. To have you wife dealing with early signs of dementia has to be overwhelming. Actually I think my wife is also showing signs but if I say anything like I just told you 10 minutes ago I’m in the dog house .i have to be careful what and when I say anything. I caught her ordering pills for memory loss but then she cancelled it , knowing it would not help even though that billionaire invested millions to develop the pill, wish you luck with all the stress.

Jump to this post

@graybeard46 I'm sorry to see this about your wife. I developed great patience with my wife. Good luck. I'll be praying for both if you

REPLY
Please sign in or register to post a reply.