Getting second lupron injection

Posted by kevtrav @kevtrav, 17 hours ago

Has anybody gone through rounds of lupron injections? I had my first shot st the end of February. I've experienced severe fatigue, mood swings, tears come easily, muscle loss, weight gain, brain fog and more. I have my second shot in early September. If you've had this, does your body handle the second shot better? Does the fatigue and side effects hit you hard again?

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Same:
I had two of the six month Lupron injections, and had most of the side effects/effects that you note. The severity of side effects for myself did not decrease with the second injection. I found the following to be helpful in limiting intensity of the side effects:
1) exercise, although difficult it helped tremendously. I walked daily and also initiated a weightlifting program.
2) Cymbalta, a pain relieving antidepressant helped significantly with hot flashes, mood swings, and situational depression. After completing Lupron I was able to withdraw completely from the drug.
3) Daily naps helped significantly as well.
4) Having a spiritual foundation was helpful. Daily scripture reading was essential for me.
5) continue to stay and engage on this forum. Lots of good useful information and encouragement. Remember the positive effects of using ADT therapy despite the short term hell we have to go through.
6) I think one of my biggest issues was weight gain. Retrospectively, I probably should have limited caloric intake significantly during ADT treatment.
Good luck, hang in there it does get better after completion.

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Is there any chance that you can switch to Orgovyx ?
My husband is on it and has zero side effects *knock the wood.
I know that "no side effects" is rarity but many members here have much better results with Orgovyx than with other ADT drugs.

Also - do you exercise every day (aerobic plus weight/resistance training) ? My husband attributes his good tolerance of ADT to exercise and Orgovyx.

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I was on Lupron for six years? I had lots of hot flashes, Muscle loss, brain fog, Bone density problems. What you describe are what a lot of people experience.

If the mood swings become a real problem and you have depression, you need to see a Doctor Who can prescribe anti-anxiety medicine medicines for you. People in this forum have mentioned the following drugs and even more for anxiety reductio.

Common drugs for depression and anxiety
Wellbutrin, Zoloft, Effexor, Buspirone, Cymbalta, Lexipro, Prozac, Celexa, Paxil, Escitalopram

Due to their different mechanisms of action. ADT which includes Orgovyx, Firmagon, Lupron, Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, and Decapeptyl can cause numerous side effects. Actually due to a lack of testosterone.
Hot flashes
Fatigue
Muscle deterioration
Bone weakening
Brain fog
Depression
Weight gain
Joint pain
Difficulty in breathing

Not all of these side effects occur to everyone on the drugs. Most of them are just things you have to be aware of and circumvent. I walk fast on a track twice a day, 1 mile at least, to help prevent bone weakening, fatigue and muscle deterioration. I also go to the gym three days a week (usually) and spend an hour with all different types of weight exercises. One thing that happens is people get a beer belly from the muscle deterioration, I do a lot of sit-ups to offset that.

Some people get depression but it is not common. It is easily treatable, according to people that have reported it on here and on Online Meetings I have participated in. If he has that problem Come back and ask for help, Or see a psychiatrist about doing something to relieve the depression.

Some people get no hot flashes at all. Others only have a few hot flashes and they are very minor. I had severe hot flashes for the first year on Lupron. As a hot flash was hitting I would feel a lot of fatigue. After a year, my oncologist prescribed a depo-provera shot every three months and it really stopped those hot flashes on Lupron. There are other hormones that can do this, speak to your doctor. If you have this problem, we can give you a list of drugs that can stop it. Ae doctor at a recent conference, put out a big list. I wear a Embrlabs.com Wave 2 device. It can reduce the hot flashes during the day and at night pretty much stops them completely. Megestrol has worked for some people.

I know one person that says eating tofu every day really controlled his hot flashes, another person in this forum said the same thing. Tofu does have properties similar to endocrine hormones but a lot weaker. Can’t hurt to try it. Seems they ate it daily.

According to a doctor that spoke to a recent webinar, many people on ADT, if they are staying on ADT for an extended period or have become castrate resistant should be taking bone straighteners. I took Fosamax for six years and I’m now on Zometa. That along with calcium taken daily helps keep your bones strong. Ask your doctor about this.

I have never gained any weight while on ADT. I get on the scale every morning and base what I eat on what I weigh. Skip lunch at times. Some people gain a lot of weight. The average is 5 pounds but some gain more and some gain none. Be aware that because you are on ADT you will find it very difficult to lose weight. That is one of the problems when you have a very little testosterone, you really have to work for it. Cutting out meals for weight loss often backfires by causing your metabolism to slow down and promoting fat storage as the body enters a survival-oriented "conservation mode". It leads to nutrient deficiencies, intense hunger causing overeating later, energy crashes, mental fatigue, and potential muscle loss.

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I don’t take Lupron but a similar med is Eligard it leaves me a rash, black an blue and a large nut like that doesn’t go away I’m on my 4th, I hopping to switch to a pill orgovix soon

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