Has anyone found a treatment that helps with peripheral neuropathy?

Posted by bigjohnscho @bigjohnscho, Jul 1, 2025

I suspect that everyone on this forum has been searching for a medication that helps their neuropathy and even though you no that all the internet claims are false we continue to waste hundreds of pounds. Desperation is a powerful force. Has any one been fortunate enough to find a genuine treatment. I just can’t believe that there are so many awful people who prey on our vulnerability and knowingly orchestrate such elaborate scams.

Interested in more discussions like this? Go to the Neuropathy Support Group.

John, Volunteer Mentor | @johnbishop | 21 hours ago

In reply to @cullerellison "New to group. Feel encouraged by the feedback." + (show)

Welcome @cullerellison, It's good to hear that you feel encouraged by what others have shared. It can be a daunting experience to say the least when you are searching for a treatment to provide some relief for your neuropathy symptoms. Not sure if you have tried the search feature of Connect, but it is great for locating others with similar symptoms to learn what they have shared helped them. Here's a search using "neuropathy what helps" that you can scan through the many different discussions and member comments - https://connect.mayoclinic.org/search/.

I shared my journey in another discussion here - https://connect.mayoclinic.org/comment/310341/.
How long have you been dealing with neuropathy?

arcuri24 | @arcuri24 | 20 hours ago

In reply to @jamessaxo "Levelup Thanks for your detailed reply. An a little sad for you. I walk briskly 5..." + (show)

@jamessaxo
I am envious for sure. I have had a nerve irritation problem due to a dermatologist's removal of a lesion on my shin that turned out not to be cancerous. This took place 7 months ago but my neurologist said that nerves heal very slowly so I may have to be patient and wait a long time to get full healing. I also have neuropathy due to my celiac disease which I am managing. I must have a mild case or else my vitamin intake is helping me along. Most times I can ignore the neuropathy but I do miss more vigorous exercise like taking long walks. I do stretching and free weights but am careful about using my left shin. So I limit tai chi plies and karate kicks. You mentioned methyl cobalamin which I take but do agree that food intake is the best way to get vitamin benefits. I was found deficient in vitamin D so have now doubled my intake and will get tested again to see if I am now in normal range.

mikead63 | @mikead63 | 18 hours ago

In reply to @crowhunter "tried it all. nothing helps." + (show)

@crowhunter Unfortunately some things work for some and some don't. When I was diagnosed with idiopathic peripheral neuropathy a few years back my "so called" brilliant Neurologist provided no suggestions or options for treatment (That was the first and last time Visited him!).

What has helped me the most is (1) Mayo Clinic Connect and the numerous wonderful people who contribute to these discussions. I've received some wonderful options for temporary side effects that have helped me sleep with no burning or pain in my feet for example. I was pointed to a number of over the counter medications that I believe have been extremely helpful. I also have learned a lot on neuropathy from articles and studies recommended by members and group mentors. (2) From the beginning I have researched the subject on the "sites" of Mayo Clinic, Cleveland Clinic, MD Anderson and others (Specifically Neuropathy related research organizations, NIH etc.) and I continue to learn on a daily basis!

Let me add one more thing about Mayo Clinic Connect. I was diagnosed with prostate cancer 10-11 years ago - at the safe level (not aggressive) where I chose active surveillance since the diagnosis. This spring testing indicated I needed to address new findings (still contained in the prostate, so far). I have followed the various prostate related discussions and have learned so much from other individuals that it helped me and my wife choose the best medical option available to me at this stage of my life. In August I will have my procedure at Mayo Rochester. Mayo is one of the few in the country who has the medical device and individuals who perform this specific procedure. I would not have known about this procedure if I was not on the prostate cancer discussions because not one of the various "specialists" I met with ever brought it up as an option, not one. And you know why? It wasn't something they could offer....