My TC journey: Taxotere (docetaxel) & Cytoxan (cyclophosphamide)

Some of you may have read my other posts about my skin reaction to the Taxotere. My 4th and final infusion is scheduled for later this morning. I have had such a bad reaction to the Taxotere which gets worse with every infusion that I am not sure I am going to finish it. My hands stay red and with skin peeling despite being on steroids before and after the last infusion. I ended up on a Medrol dose pack and it still did not help. Only now 3 weeks later has the redness and stiffness decreased a little. I can't take hot showers can only tolerate lukewarm water on my hands or it stings/burns.

My thoughts are that I am willing to take the Taxotere but at a reduced strength hoping for less of a reaction. I do not want permanent skin damage from this drug. I have gotten 3 full strength rounds. My tumor was small 1.2 cm with clear margins and lymph nodes, but tumor grade was a 3. CK-67 score was around 30-31 as far as I can remember and I had a bilateral mastectomy. I am also scared not to do the full strength will it matter that much?

Opinions anyone or advice?

I was originally doing a TC regimen for my breast cancer 3 cycles. I developed a severe skin toxicity to the Taxotere so after my 2nd infusion my Oncologist switched me to Taxol. He had me wait 2 weeks for my skin to heal from the Taxotere. The Taxol is to take the place of the last chemo infusion that I could not do with Taxotere. To lessen the side effects, he split the last infusion over 3 weeks using the Taxol instead of giving me one large dose.

After the first Taxol infusion I noticed a little bit of tingling in my fingers. I had my second infusion on 7/2 and now I have more tingling in my fingers and toes are numb and part of the upper foot by toes feels like its asleep. I go for the last infusion on 7/9. I'm wondering if this is likely to be permanent side effects or has anyone had symptoms like this go away?

I was originally doing a TC regimen for my breast cancer 3 cycles. I developed a severe skin toxicity to the Taxotere so after my 2nd infusion my Oncologist switched me to Taxol. He had me wait 2 weeks for my skin to heal from the Taxotere. The Taxol is to take the place of the last chemo infusion that I could not do with Taxotere. To lessen the side effects, he split the last infusion over 3 weeks using the Taxol instead of giving me one large dose.

After the first Taxol infusion I noticed a little bit of tingling in my fingers. I had my second infusion on 7/2 and now I have more tingling in my fingers and toes are numb and part of the upper foot by toes feels like its asleep. I go for the last infusion on 7/9. I'm wondering if this is likely to be permanent side effects or has anyone had symptoms like this go away?

I was originally doing a TC regimen for my breast cancer 3 cycles. I developed a severe skin toxicity to the Taxotere so after my 2nd infusion my Oncologist switched me to Taxol. He had me wait 2 weeks for my skin to heal from the Taxotere. The Taxol is to take the place of the last chemo infusion that I could not do with Taxotere. To lessen the side effects, he split the last infusion over 3 weeks using the Taxol instead of giving me one large dose.

After the first Taxol infusion I noticed a little bit of tingling in my fingers. I had my second infusion on 7/2 and now I have more tingling in my fingers and toes are numb and part of the upper foot by toes feels like its asleep. I go for the last infusion on 7/9. I'm wondering if this is likely to be permanent side effects or has anyone had symptoms like this go away?

I was able to tolerate all 4 Taxotere treatments but did end up with neuropathy - feet and legs, less hands. was told it would go away in a few weeks and when pressed, they said usually 10-12. Still had it after that, persistent but not worsening on the ai. Asked at 7 weeks if it I need to consider it permanent at that point and he recommended a supplement called alpha lipoic acid at 600mg twice daily. Researched it and found it does help with nerve regeneration/transmission so went on it and it helped clear about 80% of the neuropathy. Stopped at 6 months and while there was still a small amount, didn’t bother me. It has worsened some the last few months - I think because of the exemestane - but haven’t restarted the ala yet. Just now changing to letrozole so will see if it stabilizes once off the exemestane and if not will probably try the ala again (sigh, another pill).

I was originally doing a TC regimen for my breast cancer 3 cycles. I developed a severe skin toxicity to the Taxotere so after my 2nd infusion my Oncologist switched me to Taxol. He had me wait 2 weeks for my skin to heal from the Taxotere. The Taxol is to take the place of the last chemo infusion that I could not do with Taxotere. To lessen the side effects, he split the last infusion over 3 weeks using the Taxol instead of giving me one large dose.

After the first Taxol infusion I noticed a little bit of tingling in my fingers. I had my second infusion on 7/2 and now I have more tingling in my fingers and toes are numb and part of the upper foot by toes feels like its asleep. I go for the last infusion on 7/9. I'm wondering if this is likely to be permanent side effects or has anyone had symptoms like this go away?

@mistymar I'm hoping since I'm only doing the 1 Taxol infusion split over 3 weeks that this will not be permanent. The Taxol was to replace the last TC infusion.