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Getting second lupron injection

Posted by kevtrav @kevtrav, 2 days ago

Has anybody gone through rounds of lupron injections? I had my first shot st the end of February. I've experienced severe fatigue, mood swings, tears come easily, muscle loss, weight gain, brain fog and more. I have my second shot in early September. If you've had this, does your body handle the second shot better? Does the fatigue and side effects hit you hard again?

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pesquallie | @pesquallie | 4 hours ago
In reply to @brianjarvis "Did your doctor explain to you prior to the first injection that everything you just described..." + (show)
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Did your doctor explain to you prior to the first injection that everything you just described is typical with any of the ADT hormone therapies (Lupron, Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, Decapeptyl, Firmagon, and Orgovyx)?

ADT surpresses testosterone, the hormone that gives you all of your male characteristics, including strength, fitness, endurance, emotions, etc.

Your testosterone levels will be below most women’s levels, and you’ll go through what’s often referred to as “male menopause.” Many men experience these side-effects to varying degrees — some more, some less —> forgetfulness, confusion, memory loss, mood swings, emotions, fatigue, loss of libido, ED, insmnia, hot flashes, night sweats, muscle atrophy, weight gain, and more…. (I only experienced loss of libido, muscle atrophy, and mild “warm flashes”.)

The key to minimizing/avoiding ADT side-effects is a robust resistance-training exercise program. These offset the severe metabolic side-effects of low testosterone.

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@brianjarvis
I got no warnings nor were any options discussed with me. I just got the standard 44 radiation treatments and Lupron. I had severe pain from the very beginning.

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Jeff Marchi | @jeffmarc | 3 hours ago
In reply to @mjm8491 "@graybeard46 Has anyone here had a Decipher test?" + (show)
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@graybeard46
Has anyone here had a Decipher test?

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@mjm8491
it would be hard to count how many people have had the decipher test here, There are so many.

At the latest ASCO (American Society of clinical oncology) Conference, some of the Presenters used decipher as a major measure of how treatment was done.

Some medical centers used decipher on almost everybody.

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brianjarvis | @brianjarvis | 2 hours ago
In reply to @pesquallie "@brianjarvis I did all the right exercise things as I had been doing most of my..." + (show)
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@brianjarvis

I did all the right exercise things as I had been doing most of my 84 years but still had the horrible side effects I mentioned. I feel like I was allergic to Lupron. My pain level was barely tolerable and i felt I was being killed.

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@pesquallie Did they try an alternate ADT (Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, Decapeptyl, Firmagon, or Orgovyx)? Sometimes even the inert ingredients can have side-effects.

There has been much reported on the physical benefits of resistance-training exercise while on ADT. Here are just a few that I’ve bookmarked:

> Drs. Sholz and Moyad talking about exercise and hormone therapy: https://m.youtube.com/watch

> A paper on The Benefits of Exercise During Hormone Therapy: https://static1.squarespace.com/static/54c68ac6e4b06d2e36a4b8c9/t/55cb7275e4b0d97ae7ff60af/1439396469154/The+Benefits+of+Exercise+During+Hormone+Therapy_Insights+August+2015_PCRI.pdf

> A study about the benefits of exercise to counteract the adverse effects of ADT: (They describe a good resistance-training program): https://journals.lww.com/acsm-msse/fulltext/2023/04000/resistance_exercise_training_increases_muscle_mass.2.aspx
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brianjarvis | @brianjarvis | 2 hours ago
In reply to @pesquallie "@brianjarvis I got no warnings nor were any options discussed with me. I just got the..." + (show)
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@brianjarvis
I got no warnings nor were any options discussed with me. I just got the standard 44 radiation treatments and Lupron. I had severe pain from the very beginning.

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@pesquallie Interesting. My experience was totally different.

When I was initially diagnosed with PCa in April 2012 (at 56y), my first comments to my urologist were “I don’t know anything about prostate cancer so, I’ve got a zillion questions to ask before you cut anything out of me, or bombard me with radiation, or inject toxic chemicals into me……”

From that point on, we had quite a few discussions. We all worked together. Unless I fully understood what was going on and why, we didn’t do it. I had the final sign-off with any action we took. They left the choice up to me to have 20, 28, or 30 sessions. (I chose 28.)

Seems like each center had a different protocol.

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