prednisone and antibiotic use for copd, how often

Posted by lizjlb @lizjlb, Oct 7, 2025

Is it really necessary for both? I hate prednisone and the dosage is for a long time. Does anyone just take the antibiotic only? Prednisone keeps me from sleeping for one thing. Also, do you start them both or alone at first sign of a cold or wait till you get phylum and coughing. Seems like move start with sinus and then eventually turn into phylum.

Interested in more discussions like this? Go to the COPD: Chronic obstructive pulmonary disease Support Group.

Profile picture for anabelflaherty @anabelflaherty

I take them both and believe both are necessary.

Jump to this post

@anabelflaherty I cannot tolerate antibiotics . I have tendencies for C Diff attacks . In the last 18 years , I have taken 3 tablets of Bactrim. For a uti. - it worked for that . But I had blisters on my body because of the Sulfa. No other antibiotics have I tried . I know the future holds some tough decisions . I am 80 , 4 ltrs 24/7 - Have never had an exacerbation . Have never used a rescue inhaler . I have a DNR order and a refusal of any respirator use in place . Bless you all , Crystalina

REPLY
Profile picture for haveaheadache @haveaheadache

I have both COPD and Scleroderma. I was given a Symbacort inhaler while in the hospital for severe pneumonia and told to stay on it until empty.
After a few days without it I didn’t breathe as well. Asked my pulmonologist for a prescription but she said the steroids in it are dangerous due to the Scleroderma. She recommended Spiriva.
Haven’t tried it yet. Has anyone tried it and how did you like it?

Jump to this post

@haveaheadache Been on Spiriva for about 6 months-works fine but affects my voice.

REPLY

Prednisone is a lifesaver-unfortunately there are side effects-I take some sleep aids like night time Tylenol dtc.

REPLY

I take the antibiotic 3X a week. They took me off prednisone! So far, so good !!

REPLY

Has anyone been prescribed 5-10mg daily long term?

REPLY

The reason you're getting prednisone is to reduce the inflammation in your lungs from the infection. Think about it. Everytime you get an infection in your lung or lungs you will have inflammation. The only way to reduce the inflammation is prednisone.
Believe me I have been there more times than I want to remember. Take the antibiotic, prednisone and do your nebulizer and you'll be feeling better soon. If you're not feeling significantly better by the time you finish the antibiotic call your doctor so you can be seen right away.

REPLY
Profile picture for jerdonus @jerdonus

Has anyone been prescribed 5-10mg daily long term?

Jump to this post

@jerdonus yes and I’m hearing it causes high cortisol than can cause breathing problems and heart arrhythmias like PVC’s and PAC’s

REPLY
Profile picture for mummers59 @mummers59

The reason you're getting prednisone is to reduce the inflammation in your lungs from the infection. Think about it. Everytime you get an infection in your lung or lungs you will have inflammation. The only way to reduce the inflammation is prednisone.
Believe me I have been there more times than I want to remember. Take the antibiotic, prednisone and do your nebulizer and you'll be feeling better soon. If you're not feeling significantly better by the time you finish the antibiotic call your doctor so you can be seen right away.

Jump to this post

@mummers59 This is my 4th bout with antibiotics and prednisone since April
I ended up in the hospital for one night in April. I don't know what happened all of a sudden; my breathing got worse. This last medication: antibiotics for 10 days and prednisone for 40 days, 3 5mg for 10 days, then 2 a day for 10 days, then 1 a day for 10 days and 1/2 for 10 days. Right after I went to 2 a day my congestion came back. It is not down in my lungs it is above my breast. I have, like, a croupy cough that sounds dry. I also have middle lobe syndrome. Which my pulmonary said I need to get a second opinion.

REPLY

I know exactly what you're talking about. I do the same thing. I was in the hospital for eight days and on prednisone for quite a while.
I'm finally going to see my Pulmonary doctor August 5. It's long overdue and I'm sure I will get a lot of flack from my doctor.

REPLY
Profile picture for jerdonus @jerdonus

Prednisone is a lifesaver-unfortunately there are side effects-I take some sleep aids like night time Tylenol dtc.

Jump to this post

@jerdonus ,I can't tolerate Tylenol p.m.
I feel drowsy the next morning, but 5mg Melatonin and a book ,reading with a small light in bed , makes me sleepy and helps me to sleep through the night ...most of the time

REPLY
Please sign in or register to post a reply.