GAMMAPTIA MUY INICIAL O MGUS, QUE APARECE SOLO EN ORINA

Hi @piter1, welcome to Connect!

I can understand why this would leave you with questions. One thing that stands out to me is that your physician has scheduled repeat evaluation rather than urgent intervention, which may be reassuring. The waiting period can be the hardest part. Hopefully members with experience being monitored for MGUS or similar findings will share what that process was like for them.

Are you having concerning symptoms?

I’m familiar with MGUS and smoldering MM since I’m smoldering. It’s hard to wait. It gets easier. Your excess kappa cells means a single clone of plasma cells is overproducing kappa proteins. It suggests non-cancerous MGUS, a good one to have if one has to have something. I’m trying to be reassuring. I’m glad your doctor is checking labs again in 3 months. I had to wait six months! Felt like an eternity! My doctor initially thought I had MGUS but I went to a myeloma specialist who did a bone marrow biopsy. That’s really the only way to know for sure what’s going on inside the bones marrow with the plasma cells and other cells. At some point your doctor may suggest that but likely he won’t either, and just follow your lab numbers (forever). I try to find ways to distract myself while waiting for my lab results. You will too. It’s a teacher of patience. Salud!

@piter1
Welcome to Connect. I can only echo what @amberl99 and Janell have said so eloquently. You have obviously done some research. After doing my own online homework I found myself worried and frightened about progression. As time has passed, I find that I am not nearly as pessimistic as the literature suggested that I should be. Much progress has been made in treatment in the unlikely event that my MGUS should progress to Multiple Myeloma. The likelihood of progression is small as I’m sure you have read. My symptoms are manageable. I have neuropathy in my feet and that creates some unbalance. I’m 74 years old. It’s hard to know when one has competing disease what symptoms are attributable to what. I also have type two diabetes, which is well controlled and the autoimmune disease, celiac.
I am struck by how hard it is for humans who have always sought a solution for their health problems and embraced treatment, to “watch and wait.” Myself included. I want a chemical or surgical intervention and then to move on. MGUS is like the house guest who never leaves. I have learned to live with it. Not to be dismissive of the health implications, but the increased medical scrutiny qualifies me for the best diagnostic workups of anyone I know. Every six months for me now. I was diagnosed nearly five years ago and my “numbers” are almost the same as they were then. I have opted not to have a bone marrow biopsy and just watch my kappa and ratio levels. My hematologist/oncologist is comfortable with that.
I’m sorry you have joined our MGUS group but happy that you found us. There are many lovely members. Do you mind sharing if you are seen by a hematologist/oncologist? How did they find your MGUS?
Patty

Muchas gracias PATTY.- Ahora estoy pendiente de nueva valoración después del diagnóstico.- Me atiende un hematólogo.- Me la diagnosticarón tras analitica extensa de sangre y orina para valoración cardiaca después de una cirugía torácica, por alteración cadenas ligeras kappa con cociente kappa/lambda de 2,41 y pico monoclonal en banda beta, descrito como no cuantificable...- Ya te iré comentando.- Yo vengo de un proceso duro con patologías asociadas y ésto me crea un nuevo frente entre tantos.- Espero vaya todo bien.-Un abrazo