Reclast prep questions

friend 123, let us know how it goes. Our thoughts are with you.

I have had two Reclast infusions. I was advised to drink minimum of 16 ounces of water 2 hours previous and take a Tylenol. My first infusion I did have some flu like symptoms, but they only lasted for about 6 hours. The second infusion I did not have any side effects. Drink water before and after and take Tylenol. Water is the key especially since your kidneys need to clear the Reclast. I have been diagnosed with CKD and I have been able to tolerate the Reclast. I hope everything goes well for you.

Hi Everyone,
I had my first in Reclast fusion yesterday. I followed everyone’s terrific advice, hydration and Tylenol. I feel great today so far. My only concern is that I woke up with heart palpitations. I did leave a message with my doctor. I also wanted to thank folks for coaching me through this journey.

I had long lasting and moderate symptoms on my first infusion. My doctor prescribed 3 days of steroids, starting the first day. I'll put up with side effects strong bones or more important than temporary discomfort

Should a person who is going to get Reclast avoid going to dentist right before receiving it.? I know there could be dental problems so I don't want to get them. Thnk you.

I definitely recommend going to your dentist and informing them that you are getting the injections. It’s better to take care of dental problems prior to Reclast. IMHO

@friend123
Reclast can cause low calcium which could cause arrthymia feeling like palpitation. Dehydration can also cause you to feel palpitations.
I'm so glad you are having an easy experience with Reclast.
Very smart to message your md.
Thanks for posting.

My first reclast infusion is tomorrow. I have trouble drinking so much water as I have had sleeve weight loss surgery 18 years ago. Any suggestions
Wild goose14

wildgoose, call the infusion center as early as possible tomorrow morning and request IV fluids before the infusion. Explain you situation and ask if you need to call your physician to have that ordered. They might call for you or might just give you the extra fluid and the extra time
The Stanford doctor who ran the clinical trials on Reclast offers this advice.
"A opposed to administering the 5 mg of zoledronic acid in 100 mL of D5W and infusing it over 15 minutes, for the past 29 years I have had the infusion nurse at Stanford dilute it into 500 mL of NS, and to infuse the 600 mL of now diluted BP over 60 minutes. TRUST ME!! By diluting it and administrating it more slowly, it improves the renal (kidney) safety.
The othr thing I do is to instruct the infusion nurses to give the patient 650 mg of acetaminophen (Tylenol) during the infusion. Then I tell the patients to take that same dose (two regular strength tablets) with dinner and at bedtime the day of the infusion, with all 3 meals and at bedtime the day after the infusion, and a final (7th) dose with breakfast the 2nd morning after the infusion. This reduces the patient's risk of experiencing a symptomatic APR from >28% to < 1%."
endodoc
The fluids and the longer infusion are really important giving your kidneys more time to filter out the bisphosphonate.
If it is too late for all of this, I'd reschedule. You should take water with you to sip during the infusion.
Some have a difficult time with side effects. The APR is said to be an achy flu that can last a week or more.
To start out dehydrated puts you a a disadvantage that you don't need.
I hope it goes well. Let us know how you fare.

I did request the physician to give me some IV fluids first. I haven’t heard back from him yet. He did prescribe the steroids to take the day of and one each day following the infusion. He did request that the infusion Be delivered over 45 minutes to 60 minutes rather than the typical 15. I’m trying to chug the water and appreciate all of your good guidance. Thank you or let you all know how this goes today.