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Reclast prep questions

Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (29)

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wildgoose, call the infusion center as early as possible tomorrow morning and request IV fluids before the infusion. Explain you situation and ask if you need to call your physician to have that ordered. They might call for you or might just give you the extra fluid and the extra time
The Stanford doctor who ran the clinical trials on Reclast offers this advice.
"A opposed to administering the 5 mg of zoledronic acid in 100 mL of D5W and infusing it over 15 minutes, for the past 29 years I have had the infusion nurse at Stanford dilute it into 500 mL of NS, and to infuse the 600 mL of now diluted BP over 60 minutes. TRUST ME!! By diluting it and administrating it more slowly, it improves the renal (kidney) safety.
The othr thing I do is to instruct the infusion nurses to give the patient 650 mg of acetaminophen (Tylenol) during the infusion. Then I tell the patients to take that same dose (two regular strength tablets) with dinner and at bedtime the day of the infusion, with all 3 meals and at bedtime the day after the infusion, and a final (7th) dose with breakfast the 2nd morning after the infusion. This reduces the patient's risk of experiencing a symptomatic APR from >28% to < 1%."
endodoc
The fluids and the longer infusion are really important giving your kidneys more time to filter out the bisphosphonate.
If it is too late for all of this, I'd reschedule. You should take water with you to sip during the infusion.
Some have a difficult time with side effects. The APR is said to be an achy flu that can last a week or more.
To start out dehydrated puts you a a disadvantage that you don't need.
I hope it goes well. Let us know how you fare.

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Replies to "wildgoose, call the infusion center as early as possible tomorrow morning and request IV fluids before..."

@gently helpful to know this, ty, I’m still in the process of getting answers from my primary care doc but my 1st infusion has been prescribed