Fulvestrant and Kisqali

I have taken both for 4 1/2 years. Try taking the Kisqali at a different time of day, maybe at bedtime or after dinner. I take Tylenol and the allergy over-the-counter drug cetirizine (Zyrtec) for overall body soreness after Fulvestrant shots--a nurse gave me this tip! Often reactions to Kisqali calm down after a few doses. Stay in touch with your oncologist if they don't. Sometimes they will lower the dose if can be done safely. Blessings to you!

Thank you so much tessspike. Are you actually feeling reasonably normal after having taken them? Has your cancer reduced significantly ?? Has the tiredness and nausea stopped?? and how long did it take to feel better?? Paracetamol/tylenol unfortunately doesn't work for me. The Zyrtec sounds like a good idea for the soreness of my skin. Thank you so much again. To get feedback from someone who has gone through the same thing is so valuable. Wishing you all the best.

@ginny100 "Reasonably normal" is a good definition. I am told I have no active cancer these days. Often the early weeks of Kisqali can cause a "flare" of symptoms and higher markers, but things usually settle down in 3-6 months. I don't have the energy I used to, but I am also older than you and I have to allow some aging to be part of the picture. I travel, enjoy friends and family, including the activities of 10 grandchildren! I consider myself so fortunate and am very thankful for the much longer, good life these drugs are supporting.

Tessspike, That is very good to hear. I am so pleased for you. Are you over the medication or do you still have to keep up the injections and tablets??
My grand children are unfortunately not near and my husband has dementia, so it is a bit of a struggle to keep the
morale up. Tanks again for your letting me know your story.

I can only speak to the Kisqali. My oncologist took me off a few weeks ago due to severe headaches, nausea and vomiting. I handled active treatment well. Medicine management has been quite the struggle. My body does not handle them well. I am also on Letrozole which I can tolerate. My humble advise is be honest with your oncologist and look for solutions to find the best solution to ensure quality of life. All the best to you!!

@ginny100 I am metastatic so it's a lifetime of Kisqali and Fulvestrant...or whatever comes next if the Kisqali stops doing such a good job. I also get Zometa infusions every 12 weeks, but I get to stop that at 5 years. I am sorry to read about your husband. Please take care of yourself as you care for him. I am long widowed but have friends in your boat.