Anyone on Jardiance for Heart failure and your success with it

@imagine4134

That's good to hear. Can you please give more details about what you mean by "improvement with my physical well-being"? (It would be helpful to know what symptoms of HF you had before starting Jardiance and how they have perhaps improved.)

I am supposed to start on Jardiance today but I am so fearful of the side effects I read about. I am already on Entresto (24/26) and Metoprolol (12.5). Afraid Jardiance will only bring my blood pressure even lower! Also, all the serious problems down there. But then I read it is a "miracle" drug for those of us with such low EF (30 and under). Can anyone offer encouragement that I should go ahead and get started on it? This is to treat HF. I am not diabetic. Thank you.

@ejbb
I am one who will say from experience with Jardiance "go ahead" and listen to and follow the guidance of your doctors.

My EF had stayed the same for over 10 years. My heart failure (HF) doctor is very active with research. His is the director of HF and heart transplant division at Mayo Jacksonville. My EF was bouncing around 20 for over 10 years.

He put me on two different additional medications that research has shown help restructure your heart. One of those was Jardiance. I have not been on it for long couple of months but the last time my EF was checked it was 22. So slight improvement but will gladly take it.

I have had NO problems associated with Jardiance. No UTIs, rashes, etc. but I keep myself clean. Jardiance was original prescribed for diabetic but research show very promising affect of improving heart failure. I too am not a diabetic.

For me I did not see a lowering any further of blood pressure. I take both entresto and carvedilol which keep my BP low. Usually around 105/70 ish. Those medications also keep my pulse rate low. It would be in low 40s but I have a ICD/Pacemaker which the pacing is set at 70 bpm.

My Electrophysiologist told me the gold goal for me would to have my BP stay around 110/70. So I am right there even with the Jardiance which did NOT lower it.

@jc76 Oh, you have no idea how helpful your reply is to me! Thank you so very much for all the detail which is so relatable to me! I am waiting for an appointment to be scheduled with an Electrophysiologist at Mayo/Phoenix for a bi-ventricular ICD because I also have LBBB. Your reply is encouraging to me. I will start the Jardiance regimen tomorrow morning. Bless you, and I wish you continued improvement with your EF!

I am presently on Farxiga (same family of drugs). I was having UTIs before my diagnosis of hfpef. I saw a urologist and started on a vaginal estrogen 3 times a week (I’ve had breast cancer but a final use is safe, generic Hiprex ( a bladder “sanitizer” and Cranberry pills with 36 units of PACs. I have now been in Farxiga for 3 months with no UTIs.

@ejbb
Oh wow your praise of little old me makes me blush. I am just trying to pass on over 20 years of experience with ICD/Pacemakers and 3 surgeries for them. I think I have been through just about all than can happen with ICD/Pacemakers and feel should share that when ever applicable to others.

I see you are going to Mayo Phoenix. That is an excellent medical institution and you are in good hands.

I hope my EF continues to go up. I have an ablation on left ventricle to help with PVCs on 06/04/26. It is same Mayo Jacksonville electrophysiologist who I have been seeing for over 20 years and did all my previous 3 ICD/Pacemakers.

Well here's my experience with Jardiance - it was prescribed for me for mild pulmonary hypertension. I took it for a couple months, did ALL the right things with regard to cleanliness (ie. used a portable bidet, cotton underwear for instance, etc. )and I STILL got a terrible vaginal yeast infection that took two visits to my PCP, two rounds of the pill medication and prescription cream to use for two weeks after the second dr. visit. The itching and pain from swollen tissue was so bad at times I had to sit with an ice pack on "you know what" to stop the irritation. I'm not sure it is totally gone yet but needless to say I stopped Jardiance much to my disappointment. I had thought it would help me in the long run. And I don't usually have side effects to medications.

Hi all,
I entered a clinical trial with alternating use of Jardiance and a placebo. For many years, I complained of fatigue, chest heaviness, edema, shortness of breath while bending over, sudden sleepiness after a light breakfast and good night sleep, and just generally feeling blah. Also have had some other issues with arthritis and stomach. Finally got diagnosed with HFpEF. No other problems - no high blood pressure, no obesity, etc. I "think" I was on Jardiance because after two months went into a period of nothing for two weeks before going back on either the active drug or placebo and immediately had really bad edema, debilitating fatigue, etc. worse then ever before. Took almost two weeks on Lasix to feel close to my baseline. I did feel better on Jardiance (again assuming I was on it which is reasonable to assume). I had no UTIs etc as I understand they are more common in diabetics. Had to give up working due to the fatigue. Glad to know there are some other treatments but I'm on the young side so this is a bit scary. Even great doctors have trouble managing HFpEF (and HFrEF) so find someone who specializes in it. Good Luck.

I starting Jardiance about three months ago. My EF is around 30, down from 40 nine years ago. I had taken amiodarone for six years and its side effects were pretty distressing.

My blood pressure is lower with Jardiance. 92/38/52 was reported from an old hospital machine. Normally the diastolic is in the 50 to 60 range. I use a treadmill for 45 minutes every other day with an average heartrate of around 120. That's about 85% of my max of 141 figured with the 220-age guesstimate. My garmin watch computes the max differently and gives me a 75% of max estimate. I use the 15% grade and 6.5 km p hr for about half the ride, working up to it and reducing toward the end.

When I had a heart attack nine years ago, my diagnosis upon leaving the hospital was congestive heart failure with 40 EJ. It's gradually dropped to 30 as heart failure progressed.

Compared to amiodarone, I do subjectively feel better using Jardiance. I've been able to start jogging a little bit, but I live mostly in SE Asia and the heat/humidity is not outdoor exercise friendly for at least half the year. At 8am today it was 92/88. Gratefully our guest house, where my treadmill lives, has a/c and is well insulated. I lift weights and free exercise on off days.

So bottom line, I feel like I am doing better using Jardiance (Eliquis was prescribed the first time as well three months ago). My blood pressure seems low, but it does not affect my lifestyle as the amiodarone did. I have read that Jardiance can help with "restructuring the heart" but I am not sure what that entails. I have an irregular heartbeat, but my local cardiologist does not seem concerned. If Jardiance is supposed to help with that, I don't see it.

If I outlive my dogs, I will consider my treatment a success.

@jc76 Best wishes for a successful ablation! So glad we have this venue to encourage and uplift each other!