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ADT or no ADT? What should I ask my Oncolgist?

Prostate Cancer | Last Active: May 28 7:09pm | Replies (50)
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I have Advanced PC and after Chemo have been on Orgovyx for treatment for 5 years. My oncologist after testing and PSA undetectable decided to give me an Orgovyx vacation. Following discussion she is thinking of switching me to Nubeqa instead of Orgovyx once PSA rises. I would appreciate any info on this decision. Is it better?

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Replies to "I have Advanced PC and after Chemo have been on Orgovyx for treatment for 5 years...."
Jeff Marchi | @jeffmarc | May 28 11:27am

@mikejf
This is a really good switch in treatment. Orgovyx Has a lot of side effects, Nubeqa Has no side effects at all for most people. I have been on ADT for over eight years and ARPI’s for 7 years.

I am now taking both Orgovyx and Nubeqa. That has kept my PSA undetectable for the last 31 months. A couple of years ago I stopped taking Orgovyx And was just on Nubeq For eight months. My Testosterone rose to 50 and my oncologist wanted me to go back on Orgovyx because I have BRCA2. My PSA never rose above undetectable.

I know a few people, who attend ancan.org online advanced prostate cancer meetings, that are on Nubeqa alone And it works really well for them. It doesn’t last forever, People do become resistant to these drugs over time.

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