Dental work while taking Tymlos?

Posted by shocknot26 @shocknot26, May 22 10:07am

Is there risk with the anabolic medications like there is with the biophosphonates (of ONJ or other issues) when getting dental work? I need to start Tymlos, and am being told conflicting answers. Does anyone have personal experience with this? I have actually seen some studies that being on Tymlos during a procedure can actually help the jaw bone (which might make sense bc isn’t it supposed to help grow bone?). Such confusing information out there. Yes, I am asking all my doctors and dentists too;) Thanks!

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shoknot26, neither Tymlos nor Forteo carry the risk of jaw necrosis. Forteo is often given as treatment for patients with ONJ. Bisphosphonates, Prolia and Evenity carry the risk. I haven't taken Tymlos, but am on extended Forteo.
There are studies in (rats, I think) that show Forteo grows jawbone. Forteo hastens the growth and integrationof bone plugs for implants. https://pmc.ncbi.nlm.nih.gov/articles/PMC11996603/

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I’m almost finished with my Tymlos, I have 2 more months and will have completed my 2 years. I’ve gone to my dentist on a regular basis for my 6 month cleanings and also had 2 fillings replaced. Absolutely no issues. I never personally read about any dental issues while on Tymlos. Good luck !

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I am 77 and my 2025 Dexascan showed the lumbar spine at -2.5 so the ortho doctor staffing the clinic "bone fracture clinic" is recommending meds. I have been at -2.4 for years. I have been a periodontal patient for many years with cleanings every 3 months and doing everything I can. I have lost a few molars over the years and am told I am not a candidate for implants with too much bone loss for grafts, etc. I have pushed back on bi-phosphonates for that reason so the doctor is suggesting Tymlos for 2 years followed by Reclast. Am I just kicking the can down the road for 2 years since Recast is a bi-phosphonate? Has anyone had drs make a connection with OP and loss of jaw/facial bone as we age? I am struggling with a decision on meds with so many dental issues and my worst Dexa is -2.5. Incidentally, I had changed primaries so used a different dexascan prior to the -2.5. It was -3.1! I repeated it at the original and it was back to -2.5 so I feel my treatment plan for meds is being based on somewhat arbitrary data. Argh!

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Profile picture for gently @gently

shoknot26, neither Tymlos nor Forteo carry the risk of jaw necrosis. Forteo is often given as treatment for patients with ONJ. Bisphosphonates, Prolia and Evenity carry the risk. I haven't taken Tymlos, but am on extended Forteo.
There are studies in (rats, I think) that show Forteo grows jawbone. Forteo hastens the growth and integrationof bone plugs for implants. https://pmc.ncbi.nlm.nih.gov/articles/PMC11996603/

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@gently this is very interesting.

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Profile picture for margaretk @margaretk

I’m almost finished with my Tymlos, I have 2 more months and will have completed my 2 years. I’ve gone to my dentist on a regular basis for my 6 month cleanings and also had 2 fillings replaced. Absolutely no issues. I never personally read about any dental issues while on Tymlos. Good luck !

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@margaretk thanks for sharing!

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Profile picture for btichy @btichy

I am 77 and my 2025 Dexascan showed the lumbar spine at -2.5 so the ortho doctor staffing the clinic "bone fracture clinic" is recommending meds. I have been at -2.4 for years. I have been a periodontal patient for many years with cleanings every 3 months and doing everything I can. I have lost a few molars over the years and am told I am not a candidate for implants with too much bone loss for grafts, etc. I have pushed back on bi-phosphonates for that reason so the doctor is suggesting Tymlos for 2 years followed by Reclast. Am I just kicking the can down the road for 2 years since Recast is a bi-phosphonate? Has anyone had drs make a connection with OP and loss of jaw/facial bone as we age? I am struggling with a decision on meds with so many dental issues and my worst Dexa is -2.5. Incidentally, I had changed primaries so used a different dexascan prior to the -2.5. It was -3.1! I repeated it at the original and it was back to -2.5 so I feel my treatment plan for meds is being based on somewhat arbitrary data. Argh!

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@btichy thanks for sharing your experience. Sorry it’s been a struggle. This whole thing is very overwhelming! I appreciate your comment and I hope someone else can chime in with some other answers for you. Take care.

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I’ve been on Tymlos for eight months. Prior to beginning Tymlos I had implants with bone grafting in 2024. When I had my DEXA scan in 2025 I had a reading of -3.3 before starting Tymlos. I have had no problems with my existing implant or any other dental work which is quite extensive. I have not heard any thing about problems with Tymlos and my implant surgeon gave it the thumbs up.

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Profile picture for willowmena @willowmena

I’ve been on Tymlos for eight months. Prior to beginning Tymlos I had implants with bone grafting in 2024. When I had my DEXA scan in 2025 I had a reading of -3.3 before starting Tymlos. I have had no problems with my existing implant or any other dental work which is quite extensive. I have not heard any thing about problems with Tymlos and my implant surgeon gave it the thumbs up.

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@willowmena This is very reassuring. Thank you for sharing your experience with me. All the best to you!

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Profile picture for btichy @btichy

I am 77 and my 2025 Dexascan showed the lumbar spine at -2.5 so the ortho doctor staffing the clinic "bone fracture clinic" is recommending meds. I have been at -2.4 for years. I have been a periodontal patient for many years with cleanings every 3 months and doing everything I can. I have lost a few molars over the years and am told I am not a candidate for implants with too much bone loss for grafts, etc. I have pushed back on bi-phosphonates for that reason so the doctor is suggesting Tymlos for 2 years followed by Reclast. Am I just kicking the can down the road for 2 years since Recast is a bi-phosphonate? Has anyone had drs make a connection with OP and loss of jaw/facial bone as we age? I am struggling with a decision on meds with so many dental issues and my worst Dexa is -2.5. Incidentally, I had changed primaries so used a different dexascan prior to the -2.5. It was -3.1! I repeated it at the original and it was back to -2.5 so I feel my treatment plan for meds is being based on somewhat arbitrary data. Argh!

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@btichy, "[There are] far-reaching implications of osteoporosis on oral health, encompassing periodontal health, tooth loss, and jawbone density." https://pmc.ncbi.nlm.nih.gov/articles/PMC10749737/ There is substantial research and there are many notations the article.
I would think Forteo or Tymlos a far better choice for you with the dental issue and almost anyone else.
Bone decay can be caused by bisphosphonates which is worse than kicking that can, but it usually happens after longer term use.
You might look at mini implants. They are less expensive and require less bone. I don't know this dentist at all but am posting the link for information on minis.
https://www.spanishhillsdentistry.com/mini-implants-for-dentures

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Thank you for all the sharing of information. My last Dexa was -2.5 in the spine so not horrible and no fracture history or falls. However, my dental history is not good with bone loss (not a candidate for implants for that reason) and I'm expecting other extractions down the road. Because I'm so worried about the dental risk, the dr is suggesting Tymlos or Forteo for 2 years instead of Fosamax. But either one has to be followed immediately with a biphosphonate (she likes Reclast). So after 2 years of injections, I would be right back to the risk of jaw necrosis from the biphosphonate. Just doesn't seem prudent given a -2.5 Dexa. I don't want to be foolish either but my primary/gyn weren't all that concerned with a -2.4 for years. I know it's my choice so I'm thankful there's knowledgable people here to help sort it out.

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