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tanika84 avatar

Trazodone stopped working

Sleep Health | Last Active: May 10 1:53pm | Replies (5)

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Profile picture for gloaming @gloaming

I don't understand the metoprolol. ???

It's too bad you inadvertently disrupted what was working. Personally, as a person with intermittent and unpredictable insomniac tendencies, I avoid using anything except melatonin or other low-grade sleep aids that Webber and Jaimeson put out to pharmacies, and then only twice each week. I don't lie awake all hours of the night, but I do awaken inside of 4 hours often and find that 3-5 mg of melatonin taken at bedtime often makes the difference on the nights I feel I really do need to catch up some.

The only other sleep aid I have been prescribed, and that was for general, low-grade anxiety after surgeries on my heart, is zopiclone. It was hit and miss. Like all such aids, the first night is a shock to the system and it performs well. But if you repeat, or run three nights in succession, your body seems to learn to resist it. That is why I 'suffer' three nights out of every four before I will take another 3-5 mg gummy of melatonin. I want it to retain its effect, and I know that successive nights will just undo that effect..................for me.

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Replies to "I don't understand the metoprolol. ??? It's too bad you inadvertently disrupted what was working. Personally,..."

@gloaming Thank you for the response.

I don't understand the metoprolol either. My BP, before the medication, was not problematic. I have my first appointment with a sleep doctor (vs. PCP) in two days. I will ask about that.

Huh - your observation that first night of taking [a drug] is a "shock to the system", so it works well. That may explain the waning effect of the Trazodone. Similarly, repeated nightly usage of your melatonin weakens its effectiveness.. body learns to resist it.

Thanks again for the very helpful insights. I am now much better prepared to assess my options. Thank you.