what is your experience with fosamax?

Posted by donaj @donaj, Jan 24, 2025

what is your experience with fosamax?

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Profile picture for hmbrglr @hmbrglr

As this is only my 3rd week on fosamax, I have had heartburn but just on the day I take it. I follow the directions, drink plenty of water and stay in the upright position for more than 1 hour before eating or drinking anything. I wonder if I should be concerned, but as I said it has only happened on the day of my dosage .

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@hmbrglr I am on Fosomax and very unsure if it is the right drug. It has way too many downsides!! Am interested in experiences from others.

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Profile picture for susanew @susanew

I have had my share of negatives while on Fosamax. I have IBS and Fosamax has made my intestinal issues a lot more sensitive than before taking this medication. I have learned what I can and cannot tolerate while on Fosamax and avoid those foods. Usually I am very tired the day I take the dose but feel better the next day. Here is my dilemma. I already have had a year on Evenity and needed a new med after the 12 month course. After learning about possible side effects of Prolia and Reclast, I just could not take the chance. I am 75 years old and am afraid my remaining years could be devastating with the possible side effects of these drugs that stay in your system for an extended period of time. At least with Fosamax, you can stop the drug at any time. I am not thrilled with Fosamax but the way I see it, all osteoporosis drugs have theirs cons so which of all these is best for your situation? Too bad a safer medication with less severe possible side effects is not available.

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@susanew your rationale is very wise…thank you

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Profile picture for Ann Shrader @annshrader

@inlimbo reading your post raises this thought: Are you looking at the balance and absorption of nutrients? Also, if you consume alcohol, that adds to the problems related to bone health. Any alcohol! (Yikes!) There are many factors to look at that may include medications. Medications should not be the first course of action. Fosomax takes calcium out of bone to put it somewhere else does not address why the body is not producing/eliminating bone material (osteoblasts and osteoclasts).

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@annshrader I'm a military vet who was exposed to an unknown toxin in 1990. My health has been changed since then. I don't drink or do drugs or smoke. All of what you shared I already know. I have horrid gut issues with malabsorption to boot. GERD, malabsorption and roseacea which began after beginning Fosomax. along with other problems I don't care to discuss here.
I don't fit ANY textbook medical diagnoses at all. In fact, whatever I was exposed to has mimicked so many conditons and has done so for weeks and/or months then can just go away on its own. Some things however, have chosen to take up permanent residence in my body. Most if not all doctors get that deer in the headlights look if I mention anything about what happened to me so these days I typically don't. For 36 years now, I get more results from doing my own research and trial and error. I've spent a small fortune on supplements and regimens over the years I've spent copious amounts of time researching and am well versed in medical jargon for a layperson. I've resigned myself to the fact that I'm stuck with whatever was done to me for life. Osteoporosis did not go away and even though I have done everything I should be doing, it did not help my bones. ALL courtesy uncle sam. More MALE military vets now get diagnosed with osteoporosis. All of us vets have one thing in common which I won't share here because the MIC is in denial about it. Nuff said.

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Profile picture for jwmusic65 @jwmusic65

@hmbrglr I am on Fosomax and very unsure if it is the right drug. It has way too many downsides!! Am interested in experiences from others.

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@jwmusic65 When you take Fosomax, be sure to drink plenty of water and sit upright for one hour before eating anythng. That's the best advice I can give. Make sure if you're taking extra calcium to also include magnesium and potassium. But please do some research into any and all supplements needed to keep up with what Fosomax takes away or needs to help facilitate the protocol.

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Profile picture for gaylefonte7792 @gaylefonte7792

@nannygoat5I take an over the counter for bone loss and after a few months I no longer have osteoarthritis ..

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@gaylefonte7792 could you let me know what you were taking?

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Profile picture for Ann Shrader @annshrader

@inlimbo reading your post raises this thought: Are you looking at the balance and absorption of nutrients? Also, if you consume alcohol, that adds to the problems related to bone health. Any alcohol! (Yikes!) There are many factors to look at that may include medications. Medications should not be the first course of action. Fosomax takes calcium out of bone to put it somewhere else does not address why the body is not producing/eliminating bone material (osteoblasts and osteoclasts).

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@annshrader Could you please provide a reference about alendronate (Fosamax) moving calcium? I have read many research papers and credible sources of information. They all say that bisphosphonates work by slowing bone resorption. Here is just one example from the Royal Osteoporosis Society:

What does alendronate do and how does it work?
https://theros.org.uk/information-and-support/osteoporosis/treatment/alendronate/
EXCERPT: "Alendronate works by slowing down the cells that break down bone"

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Profile picture for inlimbo @inlimbo

@annshrader I'm a military vet who was exposed to an unknown toxin in 1990. My health has been changed since then. I don't drink or do drugs or smoke. All of what you shared I already know. I have horrid gut issues with malabsorption to boot. GERD, malabsorption and roseacea which began after beginning Fosomax. along with other problems I don't care to discuss here.
I don't fit ANY textbook medical diagnoses at all. In fact, whatever I was exposed to has mimicked so many conditons and has done so for weeks and/or months then can just go away on its own. Some things however, have chosen to take up permanent residence in my body. Most if not all doctors get that deer in the headlights look if I mention anything about what happened to me so these days I typically don't. For 36 years now, I get more results from doing my own research and trial and error. I've spent a small fortune on supplements and regimens over the years I've spent copious amounts of time researching and am well versed in medical jargon for a layperson. I've resigned myself to the fact that I'm stuck with whatever was done to me for life. Osteoporosis did not go away and even though I have done everything I should be doing, it did not help my bones. ALL courtesy uncle sam. More MALE military vets now get diagnosed with osteoporosis. All of us vets have one thing in common which I won't share here because the MIC is in denial about it. Nuff said.

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@inlimbo Thank you for sharing. Being proactive for one's own health is what everyone should be doing. Doctors are highly trained but one method of looking at the human body does not fit all - nor are humans all the same!

I believe that you are gifted with tenacity and willingness to do the necessary work and continue to thoughtfully look for answers. One day, you will experience the fruits of your efforts.

I recently completed a masters degree in Healthcare (industrial) engineering. It is my 4th masters degree. What I learned is that the more you learn- the more things seen the same, with some nuances.

All the best!

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Profile picture for susanew @susanew

I have had my share of negatives while on Fosamax. I have IBS and Fosamax has made my intestinal issues a lot more sensitive than before taking this medication. I have learned what I can and cannot tolerate while on Fosamax and avoid those foods. Usually I am very tired the day I take the dose but feel better the next day. Here is my dilemma. I already have had a year on Evenity and needed a new med after the 12 month course. After learning about possible side effects of Prolia and Reclast, I just could not take the chance. I am 75 years old and am afraid my remaining years could be devastating with the possible side effects of these drugs that stay in your system for an extended period of time. At least with Fosamax, you can stop the drug at any time. I am not thrilled with Fosamax but the way I see it, all osteoporosis drugs have theirs cons so which of all these is best for your situation? Too bad a safer medication with less severe possible side effects is not available.

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@susanew Although you can stop taking Fosamax at any time, it's important to know the following:
Half-Life of Fosamax: The elimination half-life of Fosamax, which contains the active ingredient alendronate sodium, is approximately 126 months. This extended half-life indicates that the drug remains in the body for a significant duration after it is taken.
Implications of the Half-Life: Long-Term Effects: Due to its long half-life, Fosamax can continue to exert its effects on bone metabolism long after the last dose is administered.

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Profile picture for daisy17 @daisy17

@susanew Although you can stop taking Fosamax at any time, it's important to know the following:
Half-Life of Fosamax: The elimination half-life of Fosamax, which contains the active ingredient alendronate sodium, is approximately 126 months. This extended half-life indicates that the drug remains in the body for a significant duration after it is taken.
Implications of the Half-Life: Long-Term Effects: Due to its long half-life, Fosamax can continue to exert its effects on bone metabolism long after the last dose is administered.

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@daisy17 I am not worried about half life. I would stop because of the side effects and how I felt when taking the meds. Please read reactions to Reclast infusions. I even joined a Facebook group to learn more about Reclast side effects with so many negative posts. I realize that some do not suffer extreme side effects but many do. At my age, I do not want to chance that I may be the unlucky one living with severe side effects. And Prolia, once you start taking it, impossible to stop with also bad side effects reported. Not too many great choices in Osteoporosis therapy.

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Profile picture for susanew @susanew

@daisy17 I am not worried about half life. I would stop because of the side effects and how I felt when taking the meds. Please read reactions to Reclast infusions. I even joined a Facebook group to learn more about Reclast side effects with so many negative posts. I realize that some do not suffer extreme side effects but many do. At my age, I do not want to chance that I may be the unlucky one living with severe side effects. And Prolia, once you start taking it, impossible to stop with also bad side effects reported. Not too many great choices in Osteoporosis therapy.

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@susanew I agree. I wish there were better drugs that could help us without the terrible side effects. I am 76 and have severe osteoporosis. I haven't fractured so I've decided not to take any of the bone meds. I hope I don't regret this decision down the road. But my options are limited because I can't take Tymlos or Forteo due to parathyroid issues. I don't want to try Evenity (too new) or Prolia (due to fracture events after stopping) and have read bisphosphonates only offer minimal benefits against fracture prevention. So I'm taking a lot of supplements and hoping to minimize more bone loss.

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