@dmdinapoli81 my mspike started at 1.5 (that’s at the level when we first tested and discovered it. That’s why I had the bmb which showed the %abnormal plasma cells that put me in the SMM catagory. Interestingly, my mspike has been 1.3 then 1.2, and lab last week was 1.1. I know that reduction in that number is only significant in that it is not rising. When it rises, or other symptoms develop, we then must investigate further. Nothing replaces the information gleaned from the BMB. That’s the gold standard of information.