@dmdinapoli81
My doctor is cautiously optimistic that it's not MM, pending scan and biopsy results. The concerning factors are the rising Kappa lambda ratio, the pressure I feel in my upper left abdomen and the fact that I didn't get full PMR relief with 25mg prednisone and the pain is actually returning in the past week. I'm also severely fatigued even with taking belsomra no matter how much I sleep. My calcium is also moderately high.

@dmdinapoli81 my mspike started at 1.5 (that’s at the level when we first tested and discovered it. That’s why I had the bmb which showed the %abnormal plasma cells that put me in the SMM catagory. Interestingly, my mspike has been 1.3 then 1.2, and lab last week was 1.1. I know that reduction in that number is only significant in that it is not rising. When it rises, or other symptoms develop, we then must investigate further. Nothing replaces the information gleaned from the BMB. That’s the gold standard of information.

@dmdinapoli81
I was diagnosed last week with SMM, but since I'm on prednisone for PMR, my blood work is somewhat understated. I'm doing a quick taper off prednisone over the next three months and then checking labs again.