First Tymlos Injection

Posted by edturner @edturner, Jul 29, 2025

Who helped you with your first injection. The speciality pharmacy said I would receive my supply from Fed Ex and to watch a video or read instructions to get help!!! I’m going to call the doctor to see if I can go to her office the first time . I want to make sure I am doing it right.

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I watched a couple of videos. Here is one.

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edturner, you'll be surprised at how easy it is. Good idea to go to the office. Wherever your take the first injection don't forget fluids first, a little salt and then watch in case you are unsteady in the beginning. Best luck to your bones with this excellent medication.

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I find that it helps to hunch over a bit so that the fat around that area bunches up. Luckily I don't have a six-pack of abs - I have no idea how I'd do an injection!

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My endocrinologist had a sample injector and had me try it in her office. It really was easy. (I haven’t started the meds yet, though, waiting to complete a year of HRT in combo with other diet and exercise approaches.)

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edturner, all the stuff the others have said! My doc offered to have me do my first injection in the office so he could guide me thru it. No reason yours should object; she's the one prescribing it and she has a vested interest in making sure you do it safely. Extra hydrating and some salty food did indeed help, and after a few shots I haven't needed those so much. I do mine after dinner so I'm usually hydrated anyway. The first few, do them at a time when you can sit comfortably for a while afterwards with nothing else to do, in case you're lightheaded or nauseous. If you are, don't freak out. It'll pass in a minute. OK, not always a minute, but almost.

If all else fails, remember that kids with diabetes begin doing their own insulin injections at around age 8. If an 8 year old can do it, so can you 😔

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Profile picture for njx58 @njx58

I watched a couple of videos. Here is one.

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@njx58 I have an important question, I saw another video saying no need to refrigerate, you said put after injecting in refrigerator. What is the recommended and i it is necessary to be always after in refrigerator? Thanks appreciate

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Also if in refrigerator how many time before it should be out room temperature? Thanks

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Profile picture for glolef @glolef

@njx58 I have an important question, I saw another video saying no need to refrigerate, you said put after injecting in refrigerator. What is the recommended and i it is necessary to be always after in refrigerator? Thanks appreciate

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@glolef Tymlos does not need to be refrigerated at all once you start a new pen. You can leave it out for 30 days - assuming your room doesn't exceed 77 degrees. If it's summer and it's warm and you don't have A/C and your room gets very warm, then you should keep it refrigerated.

I have injected with a cold pen, it's fine, you won't feel anything different. It's a tiny drop, you won't notice a difference.

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Profile picture for glolef @glolef

Also if in refrigerator how many time before it should be out room temperature? Thanks

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@glolef The manufacturer says to keep it refrigerated, until your first dose. After removing the pen from the refrigerator, ideally at least 45 minutes prior to the injection, then it is not necessary to refrigerate again. You can keep it on the shelf for the remainder of the 30 days that the manufacturer says the medication remains stable (and after which, Tymlos says to discard any remaining medication, as the ingredients can start to degrade). The only time you would consider putting it back into the refrigerator would be if you were traveling in the pen has the chance of remaining in a hot car. In that case, it is recommended that you put it in a cooler.

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Tymlos has a team of online educators who will get on Zoom and give you one-on-one instructions before your first shot or as you do your first shot. I found the person I was assigned very helpful. She also encouraged me to call her with any follow up questions. Here is a link to the page where you can sign up for an online appointment.
https://www.tymlos.com/1-on-1-support/
https://www.tymlos.com/sign-up-for-support/

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