Negative Allergy Testing - can allergies almost completely go away?

Always had sinus infections (40 years). 1.5 years ago ENT recommended NeilMed Sinus Rinse 2x/day. After my last sinus surgery, 6 hours GPS Computer guided surgery about 1 yr ago, my ENT gave me course of antibiotic 4 different times - infections came back within a month. 3 months ago, ENT added an antibiotic to the sinus rinse.
Mupirocin Ointment 2% 30g - Dissolve mupirocin with 16 sinus rinse packets of 1 gallon jug of distilled water. Flush nostril twice daily with solution.
After 6 weeks, the gunk rinsed out of sinuses was greatly reduced and I don't feel the sinus infection. At my last follow up (1 week ago), ENT mentioned that sinuses were clear. Yea, finally.

I also take Zyrtec (generic) 1x/day. If the pollen count is high, I've been ok'd to take 2.

Best Wishes,
🍀

Tagging @drsharon @sueinm @jenniferhunter and @lluth412 to see if they have any thoughts to add to the input @fourleaf had for @dnorr51 about whether allergies can possibly almost completely go away over time and no longer show up on testing.

Here is the limitation of testing. It totally depends on who does the test (did they get the skin prick deep enough), the extract used to test (is it the variation of grass that is grown in your neighborhood, what you are inhaling is a mix of two irritants but the extract is only pricking your skin with one) and finally any meds in your system might throw it off. This has happened to me when I did a skin test at one Dr office then for insurance reasons I had to go to a new Dr while I was tapering off prednisone. Dog, cat and dust mites showed up on the second but not the first. One mold showed up on the first test and not on the second.

Also you can grow out of and into allergies (my drs theory on the dog allergy was that it didn’t show up because I had a foster dog at the time so was exposed regularly which is what allergy shots do for you - expose at greater and greater strengths to get your immune system to stop reacting).

If you are miserable outside then you can just say I am allergic to something out there and I am reacting to cats. You don’t need a test because that’s a real life experience (better than a test!) Find a good Dr that will work with you to find relief!

@lisalucier I completely agree with @lluth412 - even my pulmonologist/ allergist says not all allergy tests/testers/serums are equal. In my case, I can often handle one allergen at a time, but 2 or more send me into a tailspin. For example, I can be around my daughter's dog or her guinea pigs, but not both, ans and absolutely not in her home where both live.
Yesterday we toured a bunch of old homes, most of which surely had mold. I did fine at first, but after about 2 hours my system overloaded into an asthma attackinhaler to the rescue. 5 years ago, I would not have tolerated even one of those houses.
So my non-professional observation is that allergies surely do change over time.