side effects after going off Lupron

Posted by lamer25 @lamer25, 1 day ago

What side effects (mental emotional and physical) to expect after going off a 6 month Lupron shot? Have been off for 1 month and feel mood swings, fatigue and hot flashes.

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Lupron effects including the ones you mention are due to its suppression of testosterone. You can expect to have those effects until your testosterone returns which usually takes 6 months and can be up to a year AFTER the expiration of the shot. In effect you are still on Lupron and in the process of getting off and will be for many months.

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As your testosterone level returns to normal, you will have increased sexual interest.

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My brother had a six-month Lupron shot When he had SBRT radiation. It took almost a year before things went back to normal. He was 77. Hot flashes lasted about nine months after the shot’s Give it five more minutes

The heroe study showed that testosterone comes back after about five months. A lot of it depends on age.

Here’s a link to the study
https://www.sciencedirect.com/science/article/pii/S2588931123002900

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