What medications for rheumatoid arthritis (RA) work for you?

Posted by lindaadele @lindaadele, Mar 15 1:26pm

I am going on one medication after the other for my RA and not one of them is helping me and having joint pain is really not very good any help you can give me would be much appreciated thank you very much!!!

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Profile picture for mimf @mimf

I was diagnosed with Rheumatoid Arthritis 23 years ago at age 53. I switched specialists within the first year and was then treated at Hospital for Special Surgery in Nee York City. I learned very quickly to be proactive regarding choice of specialist. It is my understanding that the standard approach to a new diagnosis is to begin treatment with the most common medications used for new patients along with pain medication if needed. Then it is a ‘see how it goes’ in the subsequent weeks and months. Each medication may or may not help. Frustrating when you try several, that can have different ways of working and your pain is still there. In the first five years from memory I was prescribed 4 or 5 different meds. This is the only way to find one that bingo! Works Well for you. You might stay on it for a time and then find it doesn’t work as well as it used to. So you go up the scale to the next med the doctor chooses for you based on your own individual symptoms. The disease can progress also leading to another choice by the doctor.
It is common to ‘go through’ several meds - don’t be discouraged. You are important to your own care. Always report any new symptoms - patient portals are great for this.

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@mimf I’ve had RA for thirty years, and I couldn’t agree more with the comment above. I was stable for many years on Plaquenil. Then it’s been a rougher ride since I started biologics. I was on anti-TNF drugs (humira, embrel, Cimzia) until I developed antibodies, then tried Rinvoq, and Actemra. Actemra is an IL 6 antagonist and it seems to be working for me now. Just keep trying. Don’t get discouraged. When the biological work they are magical, but it takes time to find what works for you. Tell your doctor exactly what you’re experiencing because truly they have no other way of knowing what’s going on. Blood tests only say so much. I feel lucky now to have a very good rheumatologist with whom I have a good rapport. I think that’s the most important thing.

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Methotex rate 20 years no problem

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I found plaquenil worked for quite some time but now I question if its affecting my eye sight. I had to wait a month before I could get my eyes tested by which time Id been off it a month so would that improve things ( if plaquenil was the problem )?? Im not game to risk finding out.

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Profile picture for tisme @tisme

I found plaquenil worked for quite some time but now I question if its affecting my eye sight. I had to wait a month before I could get my eyes tested by which time Id been off it a month so would that improve things ( if plaquenil was the problem )?? Im not game to risk finding out.

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@tisme

Issues with eye sight are a known side effect of Plaquenil. When that happens, the drug is usually discontinued, and the patient is switched to another drug.

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Profile picture for synthiaMaine @synthiame

Methotex rate 20 years no problem

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@synthiame

Did you have any dizziness, weakness, and skin rashes on Methotrexate?

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Profile picture for sweetundine @sweetundine

@mimf I’ve had RA for thirty years, and I couldn’t agree more with the comment above. I was stable for many years on Plaquenil. Then it’s been a rougher ride since I started biologics. I was on anti-TNF drugs (humira, embrel, Cimzia) until I developed antibodies, then tried Rinvoq, and Actemra. Actemra is an IL 6 antagonist and it seems to be working for me now. Just keep trying. Don’t get discouraged. When the biological work they are magical, but it takes time to find what works for you. Tell your doctor exactly what you’re experiencing because truly they have no other way of knowing what’s going on. Blood tests only say so much. I feel lucky now to have a very good rheumatologist with whom I have a good rapport. I think that’s the most important thing.

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@sweetundine

For how long have you been on Actemra and what are your side effects?
I was on Actemra but unfortunately could not tolerate it after 5 months due to very bad GI cramps. Then switched to Humira, which was much better tolerated.

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Profile picture for Alta Net @altabiznet

@synthiame

Did you have any dizziness, weakness, and skin rashes on Methotrexate?

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@altabiznet no I was lucky

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Does anyone have experience with Rituxan (Rituximab) or Remicade infusions for RA?

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my rheumy says there are other drugs besides plaquenil but they are very expensive my family doc tells me some are subsidised by the government, ( something the rheumy didnt mention).

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Profile picture for Alta Net @altabiznet

@synthiame

Did you have any dizziness, weakness, and skin rashes on Methotrexate?

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@altabiznet
I’ve been taking methotrexate since 1990 and have had no issues.

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