Did hydroxychloroquine make you nauseous with diarrhea?

Posted by kmg218 @kmg218, Feb 24 5:52am

Newly diagnosed with RA after a couple years of thinking it was OA with no meds given till now. I also have IBS and a very sensitive stomach to meds of any kind. Tried hydrochloroquine but it made me so sick. The doctor then said to try it at night and when I read it causes insomnia I didn't because I can't sleep either due to RLS....I feel like a mess and failure and don't know where to now turn as far as relief. No NSAIDS allowed so only tylenol arthritis which does nothing. Anyone else struggle with these issues and meds prescribed? thanks for any thoughts....

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Profile picture for ruralgal76 @ruralgal76

@bayhorse I got diarrhea too and sick... my rheumatologist said to drink milk with it and take it at night...i did and that worked for about 9 mos. then i was suffering again from diarrhea so quit taking it last Oct..i feel fine and cannot tell of any difference...each of us are so different...i would not want to be a dr. these days with all the options...but i do think it has a lot to do with the dr. I am wishing you good luck!! Im Irish..so maybe it will help...

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@ruralgal76 I'm about to give it another try so will do it your way with milk at night...Hope it works as my body is killing me and I need something. She was reluctant to give me methotrexate due to my reaction to the milder hydroxychloroquine. Guess I'll find out! Thanks!

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Yes for about a week but I took it with toast and some tea. No longer have any issues

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Profile picture for omnipair314 @omnipair314

Yes for about a week but I took it with toast and some tea. No longer have any issues

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@omnipair314
No. It really helped after 1 year, I took it 4 more years. Then like all good doctors she moved on. Other Dr's would not give. Took it with 1 baby aspirin.

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Been on it for a couple of months. It makes me intermittently queasy, but nothing else. It did as promised and after about two weeks my pain was barey there. I''ll take queasy over pain.

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Profile picture for purehope2022 @purehope2022

Been on it for a couple of months. It makes me intermittently queasy, but nothing else. It did as promised and after about two weeks my pain was barey there. I''ll take queasy over pain.

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@purehope2022 I'm about to try it again next week....have a wedding to go to this weekend and didn't want to feel those side effects for that. I took it for a few weeks the first time and felt no pain relief, just the nausea and diarrhea. Doctor said it could take up to 4 months before I noticed any pain relief. Hopeful this time I can deal with it and get relief like you did...thanks...

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I've been on hydroxychloroquine for years. I know it helps me because when I had to stop taking it for surgery life became a lot more miserable than usual. I take it around 6am with other pills, then go back to sleep. I hope it helps you.

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I believe that initially that can be a side effect, but usually goes away. I have been on it since September and it has been helping with painful body aches, without it not sure how much I’d be able to get done in my life.

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