tizza, I haven't taken Reclast, but have been following this thread, which may give you hope for the long run. https://connect.mayoclinic.org/discussion/reclast-side-effects/
Welcome to connect, Your post will elicit new answers as well. I think you'll hear from dannyanddebbie.

Good morning! I can relate to your on going issues since receiving your Reclast infusion. It has been 19 months since I received my Reclast infusion and I still have lasting results. Both shoulders, left foot, nausea at times and now the back sides of both legs. Some days are better than others. One can never really plan anything because one day I’m feeling better and the next day not so good. If I had this to do over again, I definitely would not have received the infusion. My endocrinologist continues to say my symptoms are not from the infusion but I think he needs his head checked. Don’t get me wrong, l am better than I was after the infusion and I go to physical therapy biweekly. I keep praying that things will improve. I find a little has to do with one’s mood; try to stay positive knowing that you are in control of your energy and emotions; it does help. My endocrinologist has sent me to various specialist doctors to see what the issue might be because he really don’t understand the medication, only my bone density! When I felt like I was just going in circles I stopped going to any doctors and just continue physical therapy and try my best to remain positive that this is not life long; I will outlive this pain! Lots of luck and try to stay positive!

I had a reclast infusion in May of 2025 as well I didn't feel the effects in my bones or anything but I believe my bone density went down cuz I noticed I had a rib fracture on an X-ray and I think there was something in my pubic bone and I had increased bone density for 2 years after using for tail and my doctor told me to do the reclast and I completely regret it I think it hurt my bones. Side note my legs have become really really weak I believe it's from my herniated disc or something neurological but part of me is kind of questioning the reclast

The nightbof the infusion I had fever and back and right rib pain. My knees a,so hurt plus my hands swelled up snd joints hurt. It is seven months noww and my knees still hurt some but the rib pain is just about gone.

I've had three RELCAST injection's over a three year period. The first infusion was the worst. At first I thought had the flu. The Pain was so bad my wife took me to the ER. As soon as I informed them I had a RELCAST injection that day they gave me a morphine shot and admitted me. The next day I was fine. The second and third infusion there was no pain. My Orthopedic physician did another DEXASCAN the third year and the bone display it was getting stronger. The reason for the RELCAST was a fractured my femur twice. My question to the doctor was why didn't the start the RELCAST after the first fracture. I never received a good answer. Good Luck.

The first fracture required four plates, 16 bolts & nuts and 200 staples. The second fractured added 2 more plates, 8 bolts & nuts, and 20 staples.

P.S. I have fallen several times after the RELCAST infusion treatments and have NOT fractured anything. The weakening of the bone is primarily due to having Type 1 Diabetes for 67 years and getting old. LOL

I’m glad to find this forum, and sad to hear that Reclast long term side effects are a thing. 63 (F), height loss of 1” in a year, -2.7 lumbar score—thus Reclast.
I’m six days out from my first infusion. Ten hours after infusion I had chills, a fever of 101, nausea and vomiting, intense shoulder pain, and overall muscle and joint pain. Couldn’t leave the house the next day. Symptoms continued and I went to ER where they insisted I probably had the flu, so tested me. Negative, of course. Also gave me a CAT scan because I had stomach pain—at least they gave me Zofran first. But the fluids I was desperate for came only 3 hours later.
Day 6, appetite poor, slight nausea, low grade fever, total exhaustion.
I feel like this isn’t getting better anytime soon. Will ask for blood work next week if there’s not significant improvement.
Interesting: I asked the infusion nurse if I could get a bag of fluids after the infusion, knowing dehydration was a possible side effect. She said they used to do that before Covid, when fluids got scarce. They never resumed them because they were expensive and “nobody died” without them.
I hear your all’s frustration about Drs insisting symptoms aren’t related. Keep pushing to be listened to. Refuse to be pushed aside.

lollyb, I wanted to like your post for the advice about refusing to be pushed aside. I don't want register as liking your painful experience with Reclast. You are close to the 6th day I hope the effects are subsiding. If there isn't significant improvement you might ask for a 5 day prednisone taper (5 day medrol pack). I've read that it is easier on the bones than continual inflammation. I wish your doctors had been able to warn you of possible side effects.

dannyandebbie, thank you, again. I'd wondered if the steroid wouldn't have to be given early in the adverse response. What was the timing of the steroid for you. Was it difficult to obtain. Are your kidneys involved.
No doubt your willingness to tell us about your experience with Reclast has saved some a similar reaction.
To hear the long term consequences is sad, and provides caution. There have been many lawsuits against Novartis because of this drug. I pray you get resolution of this long lasting pain.
We are supposed to be able to trust our doctors. Many of them actively discourage any patient research, laughing at the google "rabbit hole." Some doctors encourage research even providing links to reliable research. We tend to trust our doctors, tolerate side effects and then blame ourselves.
I hope you keep posting. It is unusual to hear long term effects. Your generosity is deeply appreciated.

I had heartburn, hip, back pain in my bones for a year after my Reclast infusion. After a year the ache and pain went away. I took all the precautions suggested before an infusion. This pain came on a month or so after the infusion. No, I haven't’ gotten a second infusion.