Oral Lichen Planus: What meds & treatments have worked for you?

Posted by hem1959 @hem1959, Sep 10, 2025

Greetings from Virginia! I was recently diagnosed with oral lichen planus. I'm an RN but had never heard of this condition before. I've seen my dentist, a dermatologist and a periodontist and still don't feel I have a viable treatment plan.
This is what I've been prescribed so far: Clobetasol Propionate ointment, 0.05% by my dentist (my dermatologist told me this was way "too strong."
Dental paste, by my dermatologist, which is the most miserable stuff to apply EVER. I've tried all the tricks, but it always gets on my tongue and cheeks when I try to apply it only to my gums. It's GROSS.
Dexamethasone mouthwash by my periodontist, just recently. This is definitely the easiest product to use -- but I can't really tell if it's helping yet. It does contain 5% alcohol, which surprises me since alcohol is supposed to be avoided.
I would truly like to find some non-traditional meds or supplements and will try increasing vitamin D and will add B12 (I already take a B complex nightly). Has anyone had success with anything else? Apple cider vinegar, other supplements?

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

Yes, I will certainly share the information. We live in an environment that makes discovering root causes very difficult, but not impossible. Knowledge is power and love is our energy source. Merry Holidays, Catharine

REPLY

I was prescribed Triamcinolone Acetonide 0.1%. It too is a dental paste and difficult to apply. I finally resorted to using Q-tips to put it on the affected areas. Apparently it has worked, as the symptoms have disappeared. But I’m told it could resurface at any time. Ugh.

REPLY
Profile picture for njh516 @njh516

Good afternoon! I could have written the first two paragraphs verbatim and actually looked to see if I had.

I went to see a periodontist after my dentist dx me. She recommended I dab Clobetasol Propionate ointment, 0.05%, on my gum line with a cotton swab for two weeks. It did help relieve some of the inflammation but only slightly. The dermatologist agreed with this tx. I also use red light therapy and Closys mouthwash. It is much more gentle and doesn’t burn. The dermatologist agreed also prescribed lidocaine gel for when the pain needs stronger treatment. I also use several things for dry mouth. None of this has fixed the problem but has calmed it down 25%-50%. Yesterday I saw my dentist for an unrelated issue. She strongly suggested I go see a functional medicine provider. She wonders if I have metal allergies from my caps. I do have nickel allergy. I will follow up with the providers she recommended. I don’t feel like I’ve made much progress over the past year. The pockets around my teeth are getting very deep. Not sure what else to do, just like you.

Jump to this post

@njh516 Hello! Thanks for the rec re: Closys mouthwash, it seems to be helping. Can you tell me more about the red-light therapy? Do you have a home unit, and if so please tell me where you got it. Is it still helping?

REPLY
Profile picture for Joanne Walen @nvshaxpur

I was prescribed Triamcinolone Acetonide 0.1%. It too is a dental paste and difficult to apply. I finally resorted to using Q-tips to put it on the affected areas. Apparently it has worked, as the symptoms have disappeared. But I’m told it could resurface at any time. Ugh.

Jump to this post

@nvshaxpur I found the dental paste to be impossible to apply without leaving a gunky, gritty film in my mouth. Glad it worked for you!

REPLY
Profile picture for hem1959 @hem1959

@njh516 Hello! Thanks for the rec re: Closys mouthwash, it seems to be helping. Can you tell me more about the red-light therapy? Do you have a home unit, and if so please tell me where you got it. Is it still helping?

Jump to this post

@hem1959 hi! I’m traveling right now. I’ll get it all together and send you the names of all that stuff in about 10 days. Hang in there!

REPLY
Profile picture for hem1959 @hem1959

@nvshaxpur I found the dental paste to be impossible to apply without leaving a gunky, gritty film in my mouth. Glad it worked for you!

Jump to this post

@hem1959 I use dental trays that I had for whitening my teeth many years ago and smear the cream in there. Walgreen type trays that you mold in hot water will work too.

REPLY
Profile picture for hem1959 @hem1959

@nvshaxpur I found the dental paste to be impossible to apply without leaving a gunky, gritty film in my mouth. Glad it worked for you!

Jump to this post

@hem1959 red light therapy has helped me. My PT let me use her husbands large machine he had for Achilles. I didn’t know the specs but it helped - he did get hot. I read red light shouldn’t. I just got
My own which is I rectangle with the spectral bands 660nm-+660nm+850nm. Which I read was what is needed. I have never gone into remission but it has helped with blisters
On my tongue.

REPLY

Hi I lichen planus oral. The advise I can offer is do not use fluoride toothpaste fund a fluoride free one. Avoid mint flavoured things. As mint aggravates it. Take tumeric it helps with inflammation. Take zinc, copper, folic acid, vitin d and b12 as we can be lacking in vitamins. Rinse mouth out after eating, I have a steroid mouth wash but my friend just uses salt water. Hope that helps all on this site.

REPLY

I have oral lichen planus. It developed a year or so after I started with LP on my back. I was given the usual variety of prescription meds to apply by my dermatologist and dentist with minimal improvement. After researching I learned that some oral medications can trigger the problem including a medication i had been taking for minor heart palpitations called metoprolol. I got an okay by my Doc to gradually wean off it and the LP on my back resolved and my OLP reduced at least 75%. My advise is to look into possible triggers and discuss with your Doc.

REPLY
Please sign in or register to post a reply.