Evenity and blood pressure?

Thank you. My endo said she preferred that I keep on Evenity to finish the course and take BP meds if needed. I am checking with my PCP to see what she thinks.

@aspirecreative thanks so much for asking this question. I will have my last dose of evenity in three weeks and was wondering why my systolic bp was increasing. I’m 81 years old and have had a broken pelvis 6years ago and a broken femur in 2024. I hesitate taking any more medications!

I had normal blood pressure until after my second shot of Evenity ? It kept rising and the staff at my cancer clinic (while getting infusions weekly for 9 months said "white coat syndrome" which made no sense. I have never been anxious about doctor visits. After 6 months of Evenity my BP spiked to 179/132 and I went to the ER. It turned out I had an aneurysm and a TIA (two days apart). The Endocrinologist immediately quit giving me Evenity and my cancer clinic stopped my infusions. They put me back on Prolia. For the record, my bone density DEXA scan showed that my bones were in worse shape after 6 months of Evenity, not better. I don't know why. I am 75 with Multiple Myeloma Cancer and 12 fractured vertebrae in my spine. Also broke 2 ribs just moving my arm a few inches as requested at the beginning of my latest bone marrow biopsy.

@carinmd452 , I’m researching this for my mom. She’s 85 and in nursing home rehab after falling and breaking her arm. It’s not healing well at all. They say it may take a year.

Due to her condition, Ortho suggests Evenity. She does have Osteoporosis, but not sure how bad. She can’t recall details. She has a number of health issues and is barely mobile. Due to her neuropathy, future falls are likely. She’s often nauseous, dizzy, in pain, has high BP spikes, anxiety, gout, etc. She says she doesn’t want to take anything for osteoporosis. She hates meds, but takes what is required. Ortho explained the statistics on having fall/fracture in the future…should I encourage her or just let it go? She doesn’t have dementia so it’s her decision. At this point I just want her comfortable.

@carinmd452 Hello,
I too have had tinnitus and sl dizziness after Evenity. I also have had numbness in my face. The doctor checked my calcium as Evenity can lower it and ionized and serum calcium were normal. I took just two months of shots and am now on a 2 month vacation from Evenity, but feel I should go back on it, due to my history of compression fractures last year. So difficult to make these decisions.

I am new t oh this forum. I was told I need to go on Evenity after doing 1 year of ReclastZ. I am very hesitant about the side effects especially every month after being injected. I am very active and I’m 68 yrs old in good health but have had a spine fracture due to a fall . Anyone out there that can give me a heads up of what I’m in for if I take the Evenity?

With romosozumab, the usual side effects are joint pain, headache, injection site stuff — not typically rising blood pressure. That said, it does carry a cardiovascular warning (heart attack, stroke), so anything like:
-BP going up month to month
-new heart-related symptoms
s something doctors take seriously even if it’s not a “classic” side effect.
Anecdotally, you’re not the only one some people do report BP creeping up while on it, even though a lot of others have zero issues.

@cheezwizard Unfortunately the Doctors office and nurses said that my Blood Pressure going up every month while on Evenity: two shots one in each arm was nothing. They totally ignored my concern as I had Low Blood Pressure until I started the Evenity shots. I stopped after 6 months as my Insurance would no longer cover it which turn out to be a blessing in disguise. I and was sad and put down for my concerns about my blood pressure going up up and up. They really did not care to hear about my BP and they told me I just had "white coat Syndrome" which was untrue as I was NOT stressed at all which was very insulting. I believe the Evenity had a Black Box warning which should stay on the med warning.

Yes, I always had low bp plus
Horrible Headaches daily after waking up, chest tightness, rib cage pain sometimes going into my back, terrible fatigue, sore stiff knees at times where I can hardly walk, greatly worsening of seasonal allergies, and went to the hospital last night where they diagnosed me with a heart murmur that I never had. Kept me overnight with loads of fluids but drs would not acknowledge possible connection to the shots. I Know that’s about when it started after two shots

Yes, I always had low bp but now it’s high after two shots. I have
Horrible Headaches daily after waking up, chest tightness, rib cage pain sometimes going into my back, terrible fatigue, sore stiff knees at times where I can hardly walk, greatly worsening of seasonal allergies, and went to the hospital last night where they diagnosed me with a heart murmur that I never had. Kept me overnight with loads of fluids but drs would not acknowledge possible connection to the shots.