Hss your loved one been prescribed Seroquel for delusions?

@hughmcguire4 , I hope you find something helpful. My understanding was that the med helped with agitation. Not preventing hallucinations, but helping keep the mind calm so it’s not as upsetting. It helped my family members but everyone is different.

@celia16 We're going to try something else from a different provider later this month.

@hughmcguire4 I too stopped the Seroquel. It didn’t help with my husband’s hallucinations either. He now takes Sertraline. It doesn’t stop the hallucinations either, but it does seem to help keep him calmer and more manageable.

@hughmcguire4

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My wife (55, Alz.) was recently started on Seroquel during a hospital stay for delusions and hallucinations. The doctor wanted to keep it low to start and avoid respiridone, which she tried for one week during the fall and it caused tremors. In the hospital, they started her on Seroquel 25 mg, 3x/day and 50mg at bedtime. After a couple weeks at home, I asked her regular psychiatrist to simplify this, and he shifted it to 50mg in morning and 75mg at night. He didn't want to move to the extended release because he wasn't sure it would be as effective over 24 hours, and we would have to increase to 150mg - the next ER available. Between the prozac and Seroquel, it has definitely helped, however, there are some ironic "consequences". They also added namenda to the aricept, so between those two medicines and the two psychiatric meds, she is able to have some more lucidity, but this is a double-edged sword.

Her delusions are not completely gone - she has *regular* delusions about me cheating on her (very common in dementia) and also just recently had a couple days of thinking she was pregnant - not as common, but not unheard of. At the same time, she's been very motivated to start driving again and get a job. I get it, she's stuck at home and angry/jealous that I get to go to work. I've tried SO many things to get her out of the house doing a variety of things, but it's hard - she's still insecure about the world. We've re-started home caregiver, and she's really not happy about that, but we don't have a choice.

Sorry, back to your original question - the Seroquel is "working" - but it's not a fix-all. I'm hesitant to keep increasing, as is the psychiatrist. I asked him about trying Dronibinol, an FDA approved synthetic canibinoid, that has been recently studied for off-label use with Alzheimer's and shows promise. Of course, there haven't been enough studies for him to feel comfortable trying, but I may push hard if things get worse. What the hell do we have to lose?