I developed a runny nose after previous shots. But after last, I got the runny nose then sore throat and a full fledged cold. Coincidence or did I catch an infectious cold. Delayed my Repatha dose for one month.
Will try another dose…
I developed a runny nose after previous shots. But after last, I got the runny nose then sore throat and a full fledged cold. Coincidence or did I catch an infectious cold. Delayed my Repatha dose for one month.
Will try another dose…
@peter800 I also had a runny nose when I started Repatha. Could not tell if it was related, but I believe yes. Used lots of tissues for a month or so then that went away and no side effects since. Been on it for just over 2 years with no side effects other than a dramatic lowering of both total cholesterol and LDL
In March of 2025 I enjoyed a miochardial infarction as a result of 95% blockage of my Ramus Intermedius artery with 85% blockage of my RCA and LAD arteries caused by excessive cholesterol and calcium plaque. The cardiologist put me on Repatha immediately and did not give me a real choice of other preventative treatment as I am allergic to statins or any other drugs that affect the pancreas.
So far, I have had zero side effects and my LDL, Triglycerides, and total cholesterol has been the lowest of my entire life of 69 years. Amazing! I just hope in the long-term, I do not develop any adverse side effects 🙏
BTW, the cardiologist placed three stents that were a buger to break up for the balloons to inflate for the stents.
I have had the same experience. I have 3 stents in my LAD artery and have been on Repatha and the anticoagulant, Brilinta, for 2 1/2 years. Repatha has not been a problem for me.
I am currently trialing off Repatha. I started the twice-weekly injection Aug. 4 and took the last one Nov. 11. I believe the side effects for me—ultimately, debilitating muscle stiffness being the worst of it—started mid-October, around the sixth injection.
At first, I didn't attribute the symptoms to Repatha; I thought I was tolerating it OK. But when the worst stiffness kicked in, where I could barely walk, it was like the symptoms I had when I was deemed statin-intolerant on Lipitor (80 mg) and then Crestor. I was then on Nexletol and Zetia for three months, but my LDL was nowhere near where they wanted it, so started Repatha.
I wish I had never taken it. Unlike statins, Repatha has a long half life. Tomorrow will be five weeks off it, and I am still experiencing symptoms, this time including back spasms.
My cardiologist said Repatha doesn't cause musculoskeletal problems, although my PCP and a neurologist say it does, that it's just not as common as with statins. So I feel like I am being gaslighted by my cardiologist and I'm currently looking for a new one. I am also going to the Mayo Clinic Statin Intolerance Clinic mid-January.
I am very worried because there don't seem to be any good options beyond statins and PCSK9 inhibitors. I wish I could tolerate Repatha. I wish I could tolerate Lipitor for that matter. My life would be so much easier. But I don't want to take something that inhibits quality of life the way that the statins and Repatha have.
I have seen comments on the forum here like, What good is having low cholesterol if you can't get out of bed? so I can't take credit for it, but that is how I feel about it too.
I am currently trialing off Repatha. I started the twice-weekly injection Aug. 4 and took the last one Nov. 11. I believe the side effects for me—ultimately, debilitating muscle stiffness being the worst of it—started mid-October, around the sixth injection.
At first, I didn't attribute the symptoms to Repatha; I thought I was tolerating it OK. But when the worst stiffness kicked in, where I could barely walk, it was like the symptoms I had when I was deemed statin-intolerant on Lipitor (80 mg) and then Crestor. I was then on Nexletol and Zetia for three months, but my LDL was nowhere near where they wanted it, so started Repatha.
I wish I had never taken it. Unlike statins, Repatha has a long half life. Tomorrow will be five weeks off it, and I am still experiencing symptoms, this time including back spasms.
My cardiologist said Repatha doesn't cause musculoskeletal problems, although my PCP and a neurologist say it does, that it's just not as common as with statins. So I feel like I am being gaslighted by my cardiologist and I'm currently looking for a new one. I am also going to the Mayo Clinic Statin Intolerance Clinic mid-January.
I am very worried because there don't seem to be any good options beyond statins and PCSK9 inhibitors. I wish I could tolerate Repatha. I wish I could tolerate Lipitor for that matter. My life would be so much easier. But I don't want to take something that inhibits quality of life the way that the statins and Repatha have.
I have seen comments on the forum here like, What good is having low cholesterol if you can't get out of bed? so I can't take credit for it, but that is how I feel about it too.
@wgr123
I feel your pain. Statins were working for me until they started attacking my pancreas. I had to be hospitalized twice for reactions to Lipitor and Zetia. My pancreas was so inflamed it almost burst and that would have been all she wrote. I'm so glad Repatha is working for me and I'm praying I don't develop any of the side effects a lot of people are experiencing.
I'll be praying for you to find a solution 🙏
@wgr123
I feel your pain. Statins were working for me until they started attacking my pancreas. I had to be hospitalized twice for reactions to Lipitor and Zetia. My pancreas was so inflamed it almost burst and that would have been all she wrote. I'm so glad Repatha is working for me and I'm praying I don't develop any of the side effects a lot of people are experiencing.
I'll be praying for you to find a solution 🙏
@ibchispas Thank you for the kind thoughts. I sincerely hope Repatha continues to be auspicious for you; it is for many, it seems.
I was on 20 mg of Lipitor for a number of years with no problem; then about 11 years ago, it was bumped up to 40 mg, still no problems. Then it was increased to 80 mg two and a half years ago. A few months into it, my LDL was 51, I believe the lowest it'd been. But then a year ago, I had an episode of muscle stiffness I could barely walk, went to an urgent care.
idk why I'm going into all this, my apologies. I really envy people who can take statins or the PCSK9 inhibitors like Repatha and Prauluent. I had open heart surgery in 2022 to repair an aortic aneurysm. It was the worst thing I've ever been through, though of course I'm glad the aneurysm was discovered and fixed and the surgery was successful.
I'm just worried about what we are going to do about my LDL. I'm hoping the trip to Mayo Clinic was provide some answers.
Thank you again, and wishing you continued success with your medication.
I’ve been injecting Repatha 2xmonth for 10 months for extremely high Lp(a) and moderately high LD. The Statins and Ezitmibe did not bring my LDL down to the recommended level until I started Repatha. Now I take less statin and take only Repatha and Ezetimibe. No issues at all.
@JustinMcClanahan my experience was that the side effects on Repatha came on a bit more slowly than with statins. For the first couple of weeks I thought I had found a chlorestrol lowering drug that I could tolerate. But, that was not to be. Once the side effects came on they were even worse than as ratings and only got worse, never better. I took it for 3 months, one week and had to quit.
I am having the same issue when I first started it. It was OK and when I took the second dose, I was starting to have immediately joint pain, shoulder pain, neck, pain, back pain, hip pain. I feel like I’m taking way too much Tylenol and it’s not helping that much. My doctor told me to stop it. I’m not gonna do a third dose. I think I’m gonna try to not take it and just start on the cholesterol medicine again and see wait till the half-life is over with and see how I feel.
I am having the same issue when I first started it. It was OK and when I took the second dose, I was starting to have immediately joint pain, shoulder pain, neck, pain, back pain, hip pain. I feel like I’m taking way too much Tylenol and it’s not helping that much. My doctor told me to stop it. I’m not gonna do a third dose. I think I’m gonna try to not take it and just start on the cholesterol medicine again and see wait till the half-life is over with and see how I feel.
@rnanne after decades of trying cholesterol lowering drugs, stopping them, starting them, stopping them, etc due to the extreme side effects, I finally said NO MORE. I decided I wasn’t going to do that to my body any more. I’m hoping the Terzepitide I’m taking now will help. I have no side effects from it. I’m going to do labs in another 2 months making it 6 months of taking it.
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I developed a runny nose after previous shots. But after last, I got the runny nose then sore throat and a full fledged cold. Coincidence or did I catch an infectious cold. Delayed my Repatha dose for one month.
Will try another dose…
@peter800 I also had a runny nose when I started Repatha. Could not tell if it was related, but I believe yes. Used lots of tissues for a month or so then that went away and no side effects since. Been on it for just over 2 years with no side effects other than a dramatic lowering of both total cholesterol and LDL
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Hug
2 ReactionsIn March of 2025 I enjoyed a miochardial infarction as a result of 95% blockage of my Ramus Intermedius artery with 85% blockage of my RCA and LAD arteries caused by excessive cholesterol and calcium plaque. The cardiologist put me on Repatha immediately and did not give me a real choice of other preventative treatment as I am allergic to statins or any other drugs that affect the pancreas.
So far, I have had zero side effects and my LDL, Triglycerides, and total cholesterol has been the lowest of my entire life of 69 years. Amazing! I just hope in the long-term, I do not develop any adverse side effects 🙏
BTW, the cardiologist placed three stents that were a buger to break up for the balloons to inflate for the stents.
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Like -
Helpful -
Hug
1 ReactionI have had the same experience. I have 3 stents in my LAD artery and have been on Repatha and the anticoagulant, Brilinta, for 2 1/2 years. Repatha has not been a problem for me.
I am currently trialing off Repatha. I started the twice-weekly injection Aug. 4 and took the last one Nov. 11. I believe the side effects for me—ultimately, debilitating muscle stiffness being the worst of it—started mid-October, around the sixth injection.
At first, I didn't attribute the symptoms to Repatha; I thought I was tolerating it OK. But when the worst stiffness kicked in, where I could barely walk, it was like the symptoms I had when I was deemed statin-intolerant on Lipitor (80 mg) and then Crestor. I was then on Nexletol and Zetia for three months, but my LDL was nowhere near where they wanted it, so started Repatha.
I wish I had never taken it. Unlike statins, Repatha has a long half life. Tomorrow will be five weeks off it, and I am still experiencing symptoms, this time including back spasms.
My cardiologist said Repatha doesn't cause musculoskeletal problems, although my PCP and a neurologist say it does, that it's just not as common as with statins. So I feel like I am being gaslighted by my cardiologist and I'm currently looking for a new one. I am also going to the Mayo Clinic Statin Intolerance Clinic mid-January.
I am very worried because there don't seem to be any good options beyond statins and PCSK9 inhibitors. I wish I could tolerate Repatha. I wish I could tolerate Lipitor for that matter. My life would be so much easier. But I don't want to take something that inhibits quality of life the way that the statins and Repatha have.
I have seen comments on the forum here like, What good is having low cholesterol if you can't get out of bed? so I can't take credit for it, but that is how I feel about it too.
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Helpful -
Hug
1 Reaction@wgr123
I feel your pain. Statins were working for me until they started attacking my pancreas. I had to be hospitalized twice for reactions to Lipitor and Zetia. My pancreas was so inflamed it almost burst and that would have been all she wrote. I'm so glad Repatha is working for me and I'm praying I don't develop any of the side effects a lot of people are experiencing.
I'll be praying for you to find a solution 🙏
@ibchispas Thank you for the kind thoughts. I sincerely hope Repatha continues to be auspicious for you; it is for many, it seems.
I was on 20 mg of Lipitor for a number of years with no problem; then about 11 years ago, it was bumped up to 40 mg, still no problems. Then it was increased to 80 mg two and a half years ago. A few months into it, my LDL was 51, I believe the lowest it'd been. But then a year ago, I had an episode of muscle stiffness I could barely walk, went to an urgent care.
idk why I'm going into all this, my apologies. I really envy people who can take statins or the PCSK9 inhibitors like Repatha and Prauluent. I had open heart surgery in 2022 to repair an aortic aneurysm. It was the worst thing I've ever been through, though of course I'm glad the aneurysm was discovered and fixed and the surgery was successful.
I'm just worried about what we are going to do about my LDL. I'm hoping the trip to Mayo Clinic was provide some answers.
Thank you again, and wishing you continued success with your medication.
-
Like -
Helpful -
Hug
1 ReactionI’ve been injecting Repatha 2xmonth for 10 months for extremely high Lp(a) and moderately high LD. The Statins and Ezitmibe did not bring my LDL down to the recommended level until I started Repatha. Now I take less statin and take only Repatha and Ezetimibe. No issues at all.
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Like -
Helpful -
Hug
2 Reactions@llynch17056
I am having the same issue when I first started it. It was OK and when I took the second dose, I was starting to have immediately joint pain, shoulder pain, neck, pain, back pain, hip pain. I feel like I’m taking way too much Tylenol and it’s not helping that much. My doctor told me to stop it. I’m not gonna do a third dose. I think I’m gonna try to not take it and just start on the cholesterol medicine again and see wait till the half-life is over with and see how I feel.
-
Like -
Helpful -
Hug
2 Reactions@rnanne after decades of trying cholesterol lowering drugs, stopping them, starting them, stopping them, etc due to the extreme side effects, I finally said NO MORE. I decided I wasn’t going to do that to my body any more. I’m hoping the Terzepitide I’m taking now will help. I have no side effects from it. I’m going to do labs in another 2 months making it 6 months of taking it.