Anyone experienced increased absolute immature granulocytes on HU?

Posted by scienceteacher @scienceteacher, Nov 24, 2025

I started 500 mg Hydroxyurea daily three weeks ago. Today my CBC showed an increase of absolute immature granulocytes from 0.01 10*3/uL to 0.03 10*3/uL. Has anyone had this happen?

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Colleen Young, Connect Director | @colleenyoung | Dec 8, 2025

@scienceteacher, what did your hematologist say? Have the levels regulated or did they have to adjust treatment? How are you doing?

scienceteacher | @scienceteacher | Dec 9, 2025

In reply to @colleenyoung "@scienceteacher, what did your hematologist say? Have the levels regulated or did they have to adjust..." + (show)

@colleenyoung She said not to be concerned since my bone marrow will react with more than just platelet level. I will be doing a blood draw next week and will see how things are.
I have absolutely no side effects from the Hydroxyurea so I'll just keep the faith that all is well.

janemc | @janemc | Dec 10, 2025

HU isn't just platelet-specific. It does fiddle with other values.

Sounds like your hematologist is keeping a good watchful eye on you!

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