@mbharris Best wishes on your upcoming surgery, you will be in good, I mean great, hands! I was never on Camzyos, had a septal myectomy at Mayo at almost 76 when my symptoms suddenly became worse. My cardiologist, from his medical literature readings and the rest of us sharing here on Connect, have learned that Camzyos helps many but not everyone. My cardiologist also said that a certain percentage (don't know the %) eventually need a septal myectomy anyway. YES! Getting it done will be very worth it!