What experience has anyone had with the Signatera blood test?

Posted by babab @babab, Aug 19, 2024

What experience has anyone had with the Signatera blood test. My results have been 0.13, 0.15, and now 0.17.

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jaxfl | @jaxfl | Oct 26 11:25am

Sample made it to Natera already. Welcome change. Leg cramps 95% gone and less fatigue. The potassium IV made a big difference.

jaxfl | @jaxfl | Nov 1 2:17pm

I now have neck and arm cramps and discomfort. And the leg cramps are back.
My signatera is still pending. I called Natera twice yesterday. 1: should be done today, call back at 2PM. 2: I called back and the lady said the previous coordinator was completely wrong. Quite frustrating as the last 3 samples were processed in five days. This sample arrived 2025-10-25. Seven days ago.

Also had skin flaking off my arm, more itching (intermittent) and many white spots.

In summary: I am a wreck currently. I tried driving to pick up a new car in GA today and after 1.45H I turned around. It is just too difficult.

jaxfl | @jaxfl | Nov 2 3:26am

10/23 signatera was negative.

Holly | @eustacia55 | Nov 2 11:18am

In reply to @jaxfl "10/23 signatera was negative." + (show)

@jaxfl Wonderful news! Hope the aches subside soon.

jaxfl | @jaxfl | Nov 2 12:59pm

In reply to @eustacia55 "@jaxfl Wonderful news! Hope the aches subside soon." + (show)

@eustacia55 Thanks! Taking the good with the bad.

141emp | @141emp | Nov 3 12:12pm

In reply to @jaxfl "@eustacia55 Thanks! Taking the good with the bad." + (show)

@jaxfl congratulations! By the way I noticed something this round with Natera. I logged in to my account with them 7 days after my blood draw and could see the result. I didn’t get a text that the result was available to view online until day 9. In the past both were happening at day 7.
Happy to say it is still non detectable, kind of expected as both pet scan and MRI were good.

jaxfl | @jaxfl | Nov 3 12:49pm

Congratulations! Great news!

Yes: Natera usually has a considerable lag between results published on the portal and notifications to patients. That is why I check daily and sometimes multiple times daily.

jaxfl | @jaxfl | Nov 4 2:19pm

For the first time ever Natera sent me a results email with the PDF attached this morning. They did not send a SMS or results available in the portal email like they did previously.

ronzee50 | @ronzee50 | Nov 5 11:11am

In reply to @jaxfl "For the first time ever Natera sent me a results email with the PDF attached this..." + (show)

@jaxfl Natera is not known for customer service. I have only had two rounds so far. They requested the second blood draw before the first results were in. I have only received SMS messages for results. The fact that you actually received an email from them is amazing. I did the same as you with my second test. I started checking the portal around the time they said the results would be available. The text message came three days later to inform me that the results were available.