What experience has anyone had with the Signatera blood test?

Posted by babab @babab, Aug 19, 2024

What experience has anyone had with the Signatera blood test. My results have been 0.13, 0.15, and now 0.17.

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My 8/27 Signatera was negative again fortunately. My 8/28 CT scan showed ground glass, mucus plugging and a few nodules < 4mm. My oncologist and Cancer Commons think this is another IRAE. Likely related to my left side sinusitis symptoms. So this negative Signatera highly likely corroborates this. My 8/27 MRI was clear and even showed the liver iron deposit (likely cause by 2X 1000MG iron IV before and during DDMVAC) resolved as did the adrenal glad atrophy (another IRAE).

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@jaxfl - Signatera it's not very effective at detecting recurrent cancer in the lung only about 40%. So trust the MRI. Ground glass nodes are typically related to a lung infection, especially at that size let me know if you would like more information about this. In the meantime it is very likely you're oncologist will simply follow via MRI for at least 6 months before they would even consider doing a biopsy.

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Most oncologists only go by phase three trials and these supplements are not there yet. But there is compelling early evidence.

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@jaxfl as someone who has developed supplements for companies I can tell you that you should not rely on any supplements to achieve efficacy for any cancer. They are generally useful to maintain good health but little beyond that. Any data generated by firms that are developing supplements is not generated with the same scrutiny as a drug trial

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Thanks! I have five or six months left. One day at a time.

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