Pseudomonas in sinuses

Posted by betsey @betsey, Jun 9, 2023

About 10 days ago sinus culture culture came back, showing I have a heavy growth of pseudomonas. Other pathogens of questionable significance also showed up, but unfortunately, the order was not written in such a way that they would identify those. I have a primary immunodeficiency, which is the reason I would be interested to know what other organisms were present but, for now, all I know is that I have pseudomonas.
My ENT prescribed Tobramycin rinses twice a day which I have been doing for about a week and unfortunately I don’t feel like I’m getting any better.

Has anyone else experienced a pseudomonas sinus infection or know about it?

What treatment did you follow?

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Profile picture for billie22 @billie22

I’ve known I had pseudomonas in my sinuses for 13 years. I was on IV antibiotics then for 3 months but they were improperly given I later learned from Infectious Disease at our hospital. It remains dormant until triggered. I knew 2 years ago it was active but couldn’t get a culture to show it. It has a neon biofilm around it. If you are getting drainage with an almost clear sticky neon color, that’s biofilm. I was again diagnosed about 3 months ago. I took Cipro for 6 weeks (recommended by the lab) and the Pseudomonas GREW. Then I was but on IVs of Impenum and that is 3 times daily for 5 weeks and my drainage is still green. I go to Infectious Disease tomorrow. I am not playing around with this any longer. It can be fatal. If it’s in your bone you need to go somewhere like Cleveland Clinic. Mine has shown up on two MRIs over the past 3 years. I have lost all my teeth but 4 with the explanation it was dry mouth! Let me know anything you know. My research said only 13% of sinus infections are this bacteria.

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@billie22
I've had it in my sinuses for 45 years. Tried IV for 12 days in hospital, antibiotics, rinses. I have drainage down my throat. It smells awful. I have bad breath. I dont know what to do.

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Profile picture for jdl2004 @jdl2004

The problem is that all the “less effective” antibiotics have contributed to the virulency of the infection over the past year giving it more strength to create a biofilm protective wall. Since writing this, I was able to get in to see an ID doctor through a cancellation that opened up and I was set up with a PICC line along with my first dose of meropenem yesterday. I also met with a new ENT who concurred with the diagnosis and treatment plan. He added a nebulizer with gentamicin and scheduled sinus surgery a week after the meropenem kicked in to ensure we eradicate this infection from every angle. Everyone I have spoken with has said they’d never heard of this infection in the sinuses except for the ID dr who said it is very rare but that the IV antibiotics would be the only effective means of eradicating it successfully and even then there is a chance it can come back. My advice to anyone is to do your research, look for support groups and have an advocate with you.

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@jdl2004
I've had Pseudomonas in my sinuses for 45 years. I am beyond frustrated. Nothing has worked.

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