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Pseudomonas in sinuses

Posted by betsey @betsey, Jun 9 3:25pm

About 10 days ago sinus culture culture came back, showing I have a heavy growth of pseudomonas. Other pathogens of questionable significance also showed up, but unfortunately, the order was not written in such a way that they would identify those. I have a primary immunodeficiency, which is the reason I would be interested to know what other organisms were present but, for now, all I know is that I have pseudomonas.
My ENT prescribed Tobramycin rinses twice a day which I have been doing for about a week and unfortunately I don’t feel like I’m getting any better.

Has anyone else experienced a pseudomonas sinus infection or know about it?

What treatment did you follow?

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Moderator
Colleen Young, Connect Director | @colleenyoung | Jun 11 8:09pm

Hi @betsey, I'm tagging @sueinmn on this discussion.
Several members talk about pseudomonas in the MAC & Bronchiectasis support group here https://connect.mayoclinic.org/group/mac-bronchiectasis/

You may wish to review this discussion:
– Pseudomonas: What antibiotic treatment worked for you?: https://connect.mayoclinic.org/discussion/pseudomonastobramycin-meropenem/

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Mentor
Sue, Volunteer Mentor | @sueinmn | Jun 11 8:19pm

@betsey Pseudomonas infections are considered "opportunists" so if you have primary immunodeficiency, it can crop up in many places. Sinuses are definitely one of them.
Unfortunately, pseudomonas is slow to respond to treatment, but for sinus involvement Tobramycin rinse is considered the "gold standard." When it was in my lungs, each antibiotic was used for at least 4 weeks before reevaluation – it took 3 months to conquer.
So I would say you need to have a little patience, but if you don't begin to feel better after 3 weeks, it is probably time for a test of the sensitivity of your strain – a second oral or injected antibiotic might need to be added. That has it's own downside because these can have their own side effects.
Are you seeing an ENT ot ID doc for this?
Sue

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1 reply
sailorgirl | @sailorgirl | Nov 3 10:11am

What ended up working for you? I'm the same and going through the same thing. the Tobr isn't working for me in sinuses..

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sailorgirl | @sailorgirl | Nov 3 10:13am
In reply to @sueinmn "@betsey Pseudomonas infections are considered "opportunists" so if you have primary immunodeficiency, it can crop up..." + (show)
@sueinmn

@betsey Pseudomonas infections are considered "opportunists" so if you have primary immunodeficiency, it can crop up in many places. Sinuses are definitely one of them.
Unfortunately, pseudomonas is slow to respond to treatment, but for sinus involvement Tobramycin rinse is considered the "gold standard." When it was in my lungs, each antibiotic was used for at least 4 weeks before reevaluation – it took 3 months to conquer.
So I would say you need to have a little patience, but if you don't begin to feel better after 3 weeks, it is probably time for a test of the sensitivity of your strain – a second oral or injected antibiotic might need to be added. That has it's own downside because these can have their own side effects.
Are you seeing an ENT ot ID doc for this?
Sue

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How long did it take to feel it was working in the sinuses? I've been on it two weeks and it weeks worse, plus now my face of swollen. I have CVID too and Myasthenia Gravis Gen.. I am about to go to the ER for help, can't get into an ID doc for weeks.

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