Yes. I have had pseudomonas off and on over 45 years. No antibiotic helped. Other bacteria were successfully treated, but this one lingered and exhausted my immune system. I finally found an ENT that has persistently treated this for the last 3 years and finally, maybe it is gone. I was sent to Infectious Diseases Specialist and they prescribed infusions of cefepime for 17 days, surgery, gentamicin irrigations for 2 weeks at a time with prednasone added, and now Levofloxine and prednisone irrigations for 2 weeks at a time. I am hopeful this will finish it off. Good luck to you.