muscle weakness from blood thinners like Eliquis

Posted by twessel @twessel, Jan 29 12:22pm

I have been taking Eliquis for paroxysmal atrial fibrillation Recently, I have experienced muscle weakness in my arms and knees. Has anyone experienced this type of issue

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Profile picture for ruth36 @ruth36

@debkuz thanks for your response, I keep telling myself when I get discouraged that there are people out there that are worse off than me… I had my primary appointment the other day and told her about my legs hurting so much and she ordered x-rays on my knees and bloodwork to see if there’s Any Inflammation.
I’m hoping it is a side effect from the medication and that once I can get off Eliquis in December, I can see a difference in my legs🙏🏻🙏🏻
But in the meantime, I know I have to keep doing what I’ve been doing as the same goes “ use it or lose it”
If it ends up to be arthritis, I don’t know What I’ll do.. I’ve tried taking Tylenol, but it doesn’t seem to help the pain. I’m afraid that I’m gonna end up not being able to walk at all.

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@ruth36 there was a suggestion to stop taking Eliquis (!?!!!!)
I just remembered by sister was put on Eliquis recently for Afib. Her cardiologist suggested an implant called Watchman instead of taking blood thinners. You can look it up to see if it fits your situation.

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I live in Oregon and a similar experience happened to me and the thing I could not understand was the lack of knowledge that Eliquis is not for everyone and their denial that that these side affects do in fact exist in some patience was astounding. My side affects included aching leg and back mussels and balance issues besides a burst artery in my colon and having the drug reversed in the operating room.(I nearly died) It has been several months since taking this poison and I am feeling a lot better. I quit this drug after 1 1/2 weeks after taking it and they told me it would take several months to completely vacate my system. Doctors need to stop saying the side effects such as aching mussels, diarrhea etc, could not be caused by Eliquis. I think they have bought into the fact that in many patience there appears to be no side affects and it works fine.

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Profile picture for seawiz33 @seawiz33

@ruth36
It seems like health care has been replaced by sick care.
I am taking Eliquis 5MG to treat afib, and my ability to move decreased 60 percent. My care team has deaf ears to my issues. I wonder if the outcome from afib without this med outweighs
the misery of taking a medication that make each day dark.

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@seawiz33 I took elquise for two years. I went down very low. , i couldn't walk up my stairs. So many side effects.
I told my doctor I didn’t want to take eliquest . He changed my meds . Two times. My doctor changed me to Multaq. I red the side effects. First words in capital letters said. May cause death. Called him. So he took me off Malta’s. I was so overdose with Metoprolol 175mg and Amiodarone. Now I take Metoprolol 25 mg for A Fib.
I now am back to my old self stairs and all. One exception, I have crushed glass spots on my lungs from taking Amiodarone. Hope this is helpful. I hoe I am the only one that has gone thru these side effects on Afib + heart problems.

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Profile picture for gloaming @gloaming

I don't think your issue is with apixaban. I have never seen anyone comment about the drug causing muscles weakness, and it doesn't appear in the literature (that I have seen). Statins, though, do cause all sorts of side-effects in people, but with muscle it's usually soreness, not weakness.
https://www.drugs.com/sfx/apixaban-side-effects.html

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I was originally on Warfarin after having a stroke, but a few years later I asked my GP if there was a better alternative. He seemed very pleased to suggest me taking Eliquis and I have been taking this for about 12 years now. Recently, I have had pains and stiffness in my legs, so I feared I was developing arthritis. X-rays showed I had osteo arthritis in my hips. but it was less severe in my knees. I was referred to a Physiotherapist for the pain. First of all, she was puzzled because the pains around my knee presented like Sciatica, but the pain started below my knees and travelled up towards my thigh, unlike the usual way that Sciatica pain travels down the leg from the lower back. I followed the program of exercises she advised but the pain around my knees became much worse and I experienced a lot of stiffness. She recommended that I have an MRI scan, as she felt the pain may be neurological resulting from the stroke. I'm still waiting for an appointment for the scan and, meanwhile I struggle to get up out of a chair, or out of bed, and my knee frequently gives way. It has got so bad that my husband bought me a mobility scooter to help me get out and about. I was so relieved to read that Eliquis might have caused me all this pain, so I shall be having a discussion with my GP soon!

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Profile picture for rebeccadixon @rebeccadixon

@ruth36 Sadly, I know exactly what you are feeling! To start my afib treatment was to take coumadin bc Eliquest was $550 per month and I liked the thought of having my blood checked while on a blood thinner. Eventually, I found generic Eliquest out of Canada for $79 per month, so I started it. Fairly soon after starting it , I began having a lot more joint pain and brief vision disturbances. I told my Doctor's nurse about my painful joints. She completely dismissed my complaint by saying that side effect ISNT ON MY LIST! It angered me so I said I dont care what your list shows. At that point, I'd only taken Eliquest for one month. Then I had the ablation and it worked but 2 days after my surgery, I got extremely sick with vomiting and diarrhea. It lasted 2 days and I thought it was covid. However, a few days later, it was a repeat of vomiting and diarrhea. I started getting suspicious of the Eliquest bc I was progressively weaker, nausea, constipation, fever up to 103, shaking and a lot of pain on the right side of my body (neck, shoulder, hip & knee). Sleeping on my right side is a favorite sleeping position but that was too painful so I slept on my back. I'd feel better for a couple days but then spin right back into vomiting and joint pain. It got so bad that I didn't want to eat and when I did eat it continued to make me nauseous. I lost 13 lbs in a month! I tried to contact my EP but was told to contact my primary care doctor or go to the ER. So after 2 Urgent care visits and 2 ER visits, it was found that my heart, kidney and liver enzymes were off the charts! I was transported by ambulance from the Urgent care center to the Hospital. The hospital ran all sorts of tests and nearly all were in the abnormal ranges, so no diagnosis could be made. The hospital wanted me to stay for a third day but I told them I was quitting Eliquest and going home! Its only been 2 weeks since then but I am getting back my health. The vomiting, diarrhea and fevers stopped. It is taking time for the nausea to stop but I am getting my appetite back just now. The way and speed that I was going downhill with Eliquest, I think I would have died. Now my blood tests are slowly getting back close to normal ranges and I am able to ride my horses again. I think the Eliquest side effects were ignored. How sad is that? What would have happened to me if I had dutifully stayed on that poison? Yikes!

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@rebeccadixon I am so glad to hear that someone else has been affected by painful muscles, just like myself. I never dreamed that all this pain I experience all up my legs, my feet and each and every toe on my left side (Weak- sided from a stroke 25 years ago) could be caused by taking Eliquis! It's such a relief to know I'm not alone in this. I struggle to climb the stairs and I have so much stiffness in my knee that I can barely stand up from a chair or get out of bed in the mornings. I'm now waiting for an MRI scan because my Physiotherapist has been very puzzled what could be causing me so much pain and thinks it might be something 'neurological'. I can't wait to tell her!

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