Hello, I was on 45mg Mitrazapine for around 8 months, I went down to 30mg, held for 6 weeks, was fine, then down to 15mg, it’s been 6 weeks and still very anxious and groggy the next day. Could 15mg be causing grogginess and anxiety? My psych said to hold 15mg for 3 weeks then go to zero.

I’m also on 50mg sertraline, I was on 100mg but tapered down to 50mg before I started the mitrazapine taper. I’m also on 6mg of Diazepam, tapered very slowly from 10mg.

I’m curious if the 15mg mitrazapine is causing me to be more anxious than?

I’ve been on mirtazapine since January 8. Started on 15 mg for sleep was on that dose for 3 months then dropped to 7.5 for 7 weeks now on 3.75 mg for two weeks.my psychiatrist as of two weeks ago put me on busiprone 10 mg twice day to help with my anxiety and to assist weaning off 3.75 mg. Has anyone just dropped 3.75 after two weeks even after busiprone has not kicked in yet?

No specific experience but tapering off schedule sounds very reasonable. Good luck.

I've been taking mirtazapine for 15 years, mostly at a dose of 15 mg. I've finally decided I'm done with the appetite and weight gain issues and want to wean myself off of it. My psychiatrist who originally prescribed it for depression is on leave. I've reduced to 7.5 as of yesterday and would like some guidance on how to proceed with tapering. I know that the length of time I've been taking it makes it more difficult to stop. Thank you to anyone who can advise about this. Thank you!

I stopped 3 days ago so far so good

yes I'm om busiprone yes its helping

Anyone experience some withdrawal once mirtazapine is stopped? First 3 nights off with little anxiety however last night harder to go to sleep. Dr prescribed Trazodone 50 mg along with buspar 10 mg twice a day for buspar.